Causes and consequences of snake venom variation
Snake venoms are mixtures of toxins that vary extensively between and within snake
species. This variability has serious consequences for the management of the world's 1.8 …
species. This variability has serious consequences for the management of the world's 1.8 …
A current perspective on snake venom composition and constituent protein families
T Tasoulis, GK Isbister - Archives of toxicology, 2023 - Springer
Snake venoms are heterogeneous mixtures of proteins and peptides used for prey
subjugation. With modern proteomics there has been a rapid expansion in our knowledge of …
subjugation. With modern proteomics there has been a rapid expansion in our knowledge of …
Phylogenetically diverse diets favor more complex venoms in North American pitvipers
The role of natural selection in the evolution of trait complexity can be characterized by
testing hypothesized links between complex forms and their functions across species …
testing hypothesized links between complex forms and their functions across species …
Micro and macroevolution of sea anemone venom phenotype
Venom is a complex trait with substantial inter-and intraspecific variability resulting from
strong selective pressures acting on the expression of many toxic proteins. However …
strong selective pressures acting on the expression of many toxic proteins. However …
Whole genome duplication and gene evolution in the hyperdiverse venomous gastropods
The diversity of venomous organisms and the toxins they produce have been increasingly
investigated, but taxonomic bias remains important. Neogastropods, a group of marine …
investigated, but taxonomic bias remains important. Neogastropods, a group of marine …
The rise of genomics in snake venom research: recent advances and future perspectives
Snake venoms represent a danger to human health, but also a gold mine of bioactive
proteins that can be harnessed for drug discovery purposes. The evolution of snakes and …
proteins that can be harnessed for drug discovery purposes. The evolution of snakes and …
Comprehensive isoform-level analysis reveals the contribution of alternative isoforms to venom evolution and repertoire diversity
Animal venom systems have emerged as valuable models for investigating how novel
polygenic phenotypes may arise from gene evolution by varying molecular mechanisms …
polygenic phenotypes may arise from gene evolution by varying molecular mechanisms …
The Tiger Rattlesnake genome reveals a complex genotype underlying a simple venom phenotype
Variation in gene regulation is ubiquitous, yet identifying the mechanisms producing such
variation, especially for complex traits, is challenging. Snake venoms provide a model …
variation, especially for complex traits, is challenging. Snake venoms provide a model …
Tracking the recruitment and evolution of snake toxins using the evolutionary context provided by the Bothrops jararaca genome
Venom is a key adaptive innovation in snakes, and how nonvenom genes were co-opted to
become part of the toxin arsenal is a significant evolutionary question. While this process …
become part of the toxin arsenal is a significant evolutionary question. While this process …
An ancient, conserved gene regulatory network led to the rise of oral venom systems
Oral venom systems evolved multiple times in numerous vertebrates, enabling the
exploitation of unique predatory niches. Yet how and when they evolved remains poorly …
exploitation of unique predatory niches. Yet how and when they evolved remains poorly …