Synthesis, spectroscopic characterization, single crystal XRD, Hirshfeld Surface analysis and theoretical studies (DFT) of 4-adamantyl-(2-(substitutedbenzylidene) …
In present work, two novel adamantyl based thiazoles were synthesized via simple
cyclization reaction of 1-(substitutedbenzylidene) thiosemicarbazides (2) and 1-adamantyl …
cyclization reaction of 1-(substitutedbenzylidene) thiosemicarbazides (2) and 1-adamantyl …
Exploring the inhibitory potential of novel bioactive compounds from mangrove actinomycetes against nsp10 the major activator of SARS-CoV-2 replication
The current study reveals the inhibitory potential of novel bioactive compounds of mangrove
actinomycetes against nsp10 of SARS-CoV-2. A total of fifty (50) novel bioactive …
actinomycetes against nsp10 of SARS-CoV-2. A total of fifty (50) novel bioactive …
The iron (III) and nickel (II) complexes with tetradentate thiosemicarbazones. Synthesis, experimental, theoretical characterization, and antiviral effect against SARS …
The discovery of new inhibitors that can be used in the treatment of viral diseases, including
Covid-19, is an area open to research, and there is a need for innovative compounds with …
Covid-19, is an area open to research, and there is a need for innovative compounds with …
Synthesized thiazole-based hydrazides and their spectral characterization along with biological studies: Promising quantum chemical insights
Hydrazide scaffold is very significant in medicinal and synthetic chemistry. Hydrazides lead
to heterocyclic pharmacophores exhibiting substantial physicochemical properties …
to heterocyclic pharmacophores exhibiting substantial physicochemical properties …
Molecular modeling and docking studies of new antioxidant pyrazole-thiazole hybrids
The phenoxyacetamide moiety was used as a link bridge in the synthesis of a series of novel
pyrazole-integrated thiazole derivatives. The condensation of the precursor 2-(4 …
pyrazole-integrated thiazole derivatives. The condensation of the precursor 2-(4 …
Spectral (FT-IR, NMR, UV) characterization, DFT studies, and molecular docking of hydrazine derivatives as antiviral agent for yellow fever (YFV)
Yellow fever virus continues to break out and claim lives in Africa and South America despite
the availability of a vaccine. Furthermore, there are reports of neurological and multiorgan …
the availability of a vaccine. Furthermore, there are reports of neurological and multiorgan …
Synthesis, characterization, antioxidant, antibacterial activity, and molecular docking studies of Zn (II) and Cu (II) complexes nanoparticles
This study involved the synthesis and characterization of a new Schiff base ligand, prepared
by reacting 3-nitrobenzaldehyde with thiourea in ethanol as the reaction medium …
by reacting 3-nitrobenzaldehyde with thiourea in ethanol as the reaction medium …
Virtual screening of potential inhibitor against breast cancer-causing estrogen receptor alpha (ERα): molecular docking and dynamic simulations
Breast cancer (Bca) causes the highest rate of mortality in females owing to the out-of-
control cell division in breast cells. In this work, we perform an in-silico screening based on …
control cell division in breast cells. In this work, we perform an in-silico screening based on …
4-Adamantyl-(2-(arylidene) hydrazinyl) thiazoles as potential antidiabetic agents: experimental and docking studies
Aim: To develop an efficient and cost-effective antidiabetic agent. Methods: A simple and
convenient Hantzsch synthetic strategy was used to prepare 4-adamantyl-(2-(arylidene) …
convenient Hantzsch synthetic strategy was used to prepare 4-adamantyl-(2-(arylidene) …
Synthesis of Thiazole‐Chalcone Hybrid Molecules: Antioxidant, Alpha (α)‐Amylase Inhibition and Docking Studies
The molecular hybrid approach is very significant to combat various drug‐resistant
disorders. A simple, convenient, and cost‐effective synthesis of thiazole‐based chalcones is …
disorders. A simple, convenient, and cost‐effective synthesis of thiazole‐based chalcones is …