The role of oxidative stress and antioxidant balance in pregnancy

T Hussain, G Murtaza, E Metwally… - Mediators of …, 2021 - Wiley Online Library
It has been widely known that oxidative stress disrupts the balance between reactive oxygen
species (ROS) and the antioxidant system in the body. During pregnancy, the physiological …

A novel and compact review on the role of oxidative stress in female reproduction

J Lu, Z Wang, J Cao, Y Chen, Y Dong - Reproductive Biology and …, 2018 - Springer
In recent years, the study of oxidative stress (OS) has become increasingly popular. In
particular, the role of OS on female fertility is very important and has been focused on …

The pivotal role of the placenta in normal and pathological pregnancies: a focus on preeclampsia, fetal growth restriction, and maternal chronic venous disease

MA Ortega, O Fraile-Martínez, C García-Montero… - Cells, 2022 - mdpi.com
The placenta is a central structure in pregnancy and has pleiotropic functions. This organ
grows incredibly rapidly during this period, acting as a mastermind behind different fetal and …

[HTML][HTML] Oxygen and oxidative stress in the perinatal period

I Torres-Cuevas, A Parra-Llorca, A Sánchez-Illana… - Redox biology, 2017 - Elsevier
Fetal life evolves in a hypoxic environment. Changes in the oxygen content in utero caused
by conditions such as pre-eclampsia or type I diabetes or by oxygen supplementation to the …

Placenta disrupted: endocrine disrupting chemicals and pregnancy

J Gingrich, E Ticiani, A Veiga-Lopez - Trends in Endocrinology & …, 2020 - cell.com
Endocrine disrupting chemicals (EDCs) are chemicals that can interfere with normal
endocrine signals. Human exposure to EDCs is particularly concerning during vulnerable …

Mechanisms of endothelial dysfunction in pre-eclampsia and gestational diabetes mellitus: windows into future cardiometabolic health?

CJ McElwain, E Tuboly, FP McCarthy… - Frontiers in …, 2020 - frontiersin.org
Placental insufficiency and adipose tissue dysregulation are postulated to play key roles in
the pathophysiology of both pre-eclampsia (PE) and gestational diabetes mellitus (GDM). A …

Early-life origins of metabolic syndrome: mechanisms and preventive aspects

CN Hsu, CY Hou, WH Hsu, YL Tain - International journal of molecular …, 2021 - mdpi.com
One of the leading global public-health burdens is metabolic syndrome (MetS), despite the
many advances in pharmacotherapies. MetS, now known as “developmental origins of …

[HTML][HTML] The endocrine disruption of prenatal phthalate exposure in mother and offspring

Y Qian, H Shao, X Ying, W Huang, Y Hua - Frontiers in public health, 2020 - frontiersin.org
Phthalates are a group of ubiquitous synthetic endocrine-disrupting chemicals. Fetal and
neonatal periods are particularly susceptible to endocrine disorders, which prenatal …

Longitudinal intravital imaging of mouse placenta

X Zhu, Q Huang, L Jiang, VT Nguyen, T Vu… - Science …, 2024 - science.org
Studying placental functions is crucial for understanding pregnancy complications. However,
imaging placenta is challenging due to its depth, volume, and motion distortions. In this …

The role of dietary polyphenols in pregnancy and pregnancy-related disorders

M Nacka-Aleksić, A Pirković, A Vilotić, Ž Bojić-Trbojević… - Nutrients, 2022 - mdpi.com
Polyphenols are a group of phytochemicals with extensive biological functions and health-
promoting potential. These compounds are present in most foods of plant origin and their …