Advances in micro-CT imaging of small animals

DP Clark, CT Badea - Physica Medica, 2021 - Elsevier
Purpose Micron-scale computed tomography (micro-CT) imaging is a ubiquitous, cost-
effective, and non-invasive three-dimensional imaging modality. We review recent …

Opportunities for new CT contrast agents to maximize the diagnostic potential of emerging spectral CT technologies

BM Yeh, PF FitzGerald, PM Edic, JW Lambert… - Advanced drug delivery …, 2017 - Elsevier
The introduction of spectral CT imaging in the form of fast clinical dual-energy CT enabled
contrast material to be differentiated from other radiodense materials, improved lesion …

In vivo whole brain microvascular imaging in mice using transcranial 3D ultrasound localization microscopy

O Demeulenaere, A Bertolo, S Pezet, N Ialy-Radio… - …, 2022 - thelancet.com
Background Non-invasive high-resolution imaging of the cerebral vascular anatomy and
function is key for the study of intracranial aneurysms, stenosis, arteriovenous …

Whole-brain vasculature reconstruction at the single capillary level

AP Di Giovanna, A Tibo, L Silvestri, MC Müllenbroich… - Scientific reports, 2018 - nature.com
The distinct organization of the brain's vascular network ensures that it is adequately
supplied with oxygen and nutrients. However, despite this fundamental role, a detailed …

DNA-AgNC loaded liposomes for measuring cerebral blood flow using two-photon fluorescence correlation spectroscopy

X Wang, MB Liisberg, GL Nolt, X Fu, C Cerretani, L Li… - ACS …, 2023 - ACS Publications
Unraveling the transport of drugs and nanocarriers in cerebrovascular networks is important
for pharmacokinetic and hemodynamic studies but is challenging due to the complexity of …

Evaluation of X‐ray tomography contrast agents: A review of production, protocols, and biological applications

MM Koç, N Aslan, AP Kao… - Microscopy research and …, 2019 - Wiley Online Library
X‐ray computed tomography is a strong tool that finds many applications both in medical
applications and in the investigation of biological and nonbiological samples. In the clinics …

4D microvascular imaging based on ultrafast Doppler tomography

C Demené, E Tiran, LA Sieu, A Bergel, JL Gennisson… - Neuroimage, 2016 - Elsevier
Abstract 4D ultrasound microvascular imaging was demonstrated by applying ultrafast
Doppler tomography (UFD-T) to the imaging of brain hemodynamics in rodents. In vivo real …

Liposome-based probes for molecular imaging: from basic research to the bedside

Y **a, C Xu, X Zhang, P Ning, Z Wang, J Tian, X Chen - Nanoscale, 2019 - pubs.rsc.org
Molecular imaging is very important in disease diagnosis and prognosis. Liposomes are
excellent carriers for different types of molecular imaging probes. In this work, we summarize …

Functional imaging of tumor vasculature using iodine and gadolinium-based nanoparticle contrast agents: a comparison of spectral micro-CT using energy integrating …

CT Badea, DP Clark, M Holbrook… - Physics in Medicine …, 2019 - iopscience.iop.org
Advances in computed tomography (CT) hardware have propelled the development of novel
CT contrast agents. In particular, the spectral capabilities of x-ray CT can facilitate …

Hierarchical imaging and computational analysis of three-dimensional vascular network architecture in the entire postnatal and adult mouse brain

T Wälchli, J Bisschop, A Miettinen, A Ulmann-Schuler… - Nature protocols, 2021 - nature.com
The formation of new blood vessels and the establishment of vascular networks are crucial
during brain development, in the adult healthy brain, as well as in various diseases of the …