Chemotherapy-induced peripheral neuropathy: part 1—current state of knowledge and perspectives for pharmacotherapy
K Sałat - Pharmacological reports, 2020 - Springer
Background Despite the increasing knowledge of the etiology of neuropathic pain, this type
of chronic pain is resistant to available analgesics in approximately 50% of patients and …
of chronic pain is resistant to available analgesics in approximately 50% of patients and …
Taxane‐induced neurotoxicity: Pathophysiology and therapeutic perspectives
Taxane‐derived drugs are antineoplastic agents used for the treatment of highly common
malignancies. Paclitaxel and docetaxel are the most commonly used taxanes; however …
malignancies. Paclitaxel and docetaxel are the most commonly used taxanes; however …
[HTML][HTML] Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway
C Wu, H Chen, R Zhuang, H Zhang… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Spinal cord injury (SCI) results in a wide range of disabilities. Its complex pathophysiological
process limits the effectiveness of many clinical treatments. Betulinic acid (BA) has been …
process limits the effectiveness of many clinical treatments. Betulinic acid (BA) has been …
Targeting T-type/CaV3. 2 channels for chronic pain
T-type calcium channels regulate neuronal excitability and are important contributors of pain
processing. CaV3. 2 channels are the major isoform expressed in nonpeptidergic and …
processing. CaV3. 2 channels are the major isoform expressed in nonpeptidergic and …
[HTML][HTML] Targeting mitochondrial ion channels for cancer therapy
Pharmacological targeting of mitochondrial ion channels is emerging as a promising
approach to eliminate cancer cells; as most of these channels are differentially expressed …
approach to eliminate cancer cells; as most of these channels are differentially expressed …
The Ca2+ channel ORAI1 is a regulator of oral cancer growth and nociceptive pain
Oral cancer causes pain associated with cancer progression. We report here that the
function of the Ca2+ channel ORAI1 is an important regulator of oral cancer pain. ORAI1 …
function of the Ca2+ channel ORAI1 is an important regulator of oral cancer pain. ORAI1 …
Cheminformatics-based study identifies potential ebola VP40 inhibitors
The Ebola virus (EBOV) is still highly infectious and causes severe hemorrhagic fevers in
primates. However, there are no regulatorily approved drugs against the Ebola virus disease …
primates. However, there are no regulatorily approved drugs against the Ebola virus disease …
Advances in CD73 inhibitors for immunotherapy: antibodies, synthetic small molecule compounds, and natural compounds
M Zhang, X Dai, Y **ang, L **e, M Sun, J Shi - European Journal of …, 2023 - Elsevier
Tumors, a disease with a high mortality rate worldwide, have become a serious threat to
human health. Exonucleotide-5′-nucleotidase (CD73) is an emerging target for tumor …
human health. Exonucleotide-5′-nucleotidase (CD73) is an emerging target for tumor …
Exosomal USP13 derived from microvascular endothelial cells regulates immune microenvironment and improves functional recovery after spinal cord injury by …
X Ge, Z Zhou, S Yang, W Ye, Z Wang, J Wang, C **ao… - Cell & Bioscience, 2023 - Springer
Spinal cord injury (SCI) can result in irreversible sensory and motor disability with no
effective treatment currently. After SCI, infiltrated macrophages accumulate in epicenter …
effective treatment currently. After SCI, infiltrated macrophages accumulate in epicenter …
Complementary and alternative medicine for painful peripheral neuropathy
V Baute, D Zelnik, J Curtis, F Sadeghifar - Current Treatment Options in …, 2019 - Springer
Purpose of review The purpose of our manuscript is to review the current evidence
supporting the use of complementary and alternative medicine (CAM) in neuromuscular …
supporting the use of complementary and alternative medicine (CAM) in neuromuscular …