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RNA‐binding proteins in pain
PR Smith, ZT Campbell - Wiley Interdisciplinary Reviews: RNA, 2024 - Wiley Online Library
RNAs are meticulously controlled by proteins. Through direct and indirect associations,
every facet in the brief life of an mRNA is subject to regulation. R NA‐b inding p roteins …
every facet in the brief life of an mRNA is subject to regulation. R NA‐b inding p roteins …
A compendium of validated pain genes
E Wistrom, R Chase, PR Smith… - WIREs Mechanisms of …, 2022 - Wiley Online Library
The development of novel pain therapeutics hinges on the identification and rigorous
validation of potential targets. Model organisms provide a means to test the involvement of …
validation of potential targets. Model organisms provide a means to test the involvement of …
Reversal of RNA toxicity in myotonic dystrophy via a decoy RNA-binding protein with high affinity for expanded CUG repeats
L Arandel, M Matloka, AF Klein, F Rau… - Nature Biomedical …, 2022 - nature.com
Abstract Myotonic dystrophy type 1 (DM1) is an RNA-dominant disease whose pathogenesis
stems from the functional loss of muscleblind-like RNA-binding proteins (RBPs), which …
stems from the functional loss of muscleblind-like RNA-binding proteins (RBPs), which …
Global analyses of mRNA expression in human sensory neurons reveal eIF5A as a conserved target for inflammatory pain
Nociceptors are a type of sensory neuron that are integral to most forms of pain. Targeted
disruption of nociceptor sensitization affords unique opportunities to prevent pain. An …
disruption of nociceptor sensitization affords unique opportunities to prevent pain. An …
[HTML][HTML] RNA binding proteins (RBPs) on genetic stability and diseases
AT Aborode, OA Abass, S Nasiru, MU Eigbobo… - Global Medical …, 2024 - Elsevier
RNA-binding proteins (RBPs) are integral components of cellular machinery, playing crucial
roles in the regulation of gene expression and maintaining genetic stability. Their …
roles in the regulation of gene expression and maintaining genetic stability. Their …
CRISPR Based Programmable RNA Editing in Primary Hippocampal Neurons
Investigating the RNA regulation landscape primarily relies on understanding how RNA‐
protein interactions are governed in various cell types, including neurons. Analysis of RNA …
protein interactions are governed in various cell types, including neurons. Analysis of RNA …
[PDF][PDF] Viral Hijacking of Host RNA-Binding Proteins: Implications for Viral Replication and Pathogenesis
NNT Cyrielle, MK Chanelle, AS ANDIGEMA - 2024 - preprints.org
In the intricate dance between viruses and host cells, RNA-binding proteins (RBPs) serve as
crucial orchestrators of gene expression and cellular processes. We will delve into the …
crucial orchestrators of gene expression and cellular processes. We will delve into the …
CRISPR based programmable RNA editing in primary neurons
K Ravichandran, T Khargonkar, S Samaddar… - bioRxiv, 2023 - biorxiv.org
Investigating the RNA regulation landscape primarily relies on our understanding of how
RNA-protein interactions are governed in various cell types, including neurons. Analysis of …
RNA-protein interactions are governed in various cell types, including neurons. Analysis of …