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Structural biology of SARS-CoV-2: open the door for novel therapies
W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
SARS-CoV-2 accessory proteins in viral pathogenesis: knowns and unknowns
There are still many unanswered questions concerning viral SARS-CoV-2 pathogenesis in
COVID-19. Accessory proteins in SARS-CoV-2 consist of eleven viral proteins whose roles …
COVID-19. Accessory proteins in SARS-CoV-2 consist of eleven viral proteins whose roles …
[HTML][HTML] ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation
G Miao, H Zhao, Y Li, M Ji, Y Chen, Y Shi, Y Bi… - Developmental cell, 2021 - cell.com
Autophagy acts as a cellular surveillance mechanism to combat invading pathogens.
Viruses have evolved various strategies to block autophagy and even subvert it for their …
Viruses have evolved various strategies to block autophagy and even subvert it for their …
SARS-CoV-2 virulence factor ORF3a blocks lysosome function by modulating TBC1D5-dependent Rab7 GTPase cycle
Abstract SARS-CoV-2, the causative agent of COVID-19, uses the host endolysosomal
system for entry, replication, and egress. Previous studies have shown that the SARS-CoV-2 …
system for entry, replication, and egress. Previous studies have shown that the SARS-CoV-2 …
Roles and functions of SARS-CoV-2 proteins in host immune evasion
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evades the host immune
system through a variety of regulatory mechanisms. The genome of SARS-CoV-2 encodes …
system through a variety of regulatory mechanisms. The genome of SARS-CoV-2 encodes …
A detailed overview of immune escape, antibody escape, partial vaccine escape of SARS-CoV-2 and their emerging variants with escape mutations
The infective SARS-CoV-2 is more prone to immune escape. Presently, the significant
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …
Evolutionary trajectory of SARS-CoV-2 and emerging variants
The emergence of a novel coronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), and more recently, the independent evolution of multiple SARS-CoV-2 …
(SARS-CoV-2), and more recently, the independent evolution of multiple SARS-CoV-2 …
Understanding the role of SARS-CoV-2 ORF3a in viral pathogenesis and COVID-19
The ongoing SARS-CoV-2 pandemic has shocked the world due to its persistence, COVID-
19-related morbidity and mortality, and the high mutability of the virus. One of the major …
19-related morbidity and mortality, and the high mutability of the virus. One of the major …
The global epidemic of SARS‐CoV‐2 variants and their mutational immune escape
D Tian, YH Sun, JM Zhou, Q Ye - Journal of medical virology, 2022 - Wiley Online Library
During the COVID‐19 pandemic, genetic variants of SARS‐CoV‐2 have been emerging and
spreading around the world. Several SARS‐CoV‐2 endemic variants were found in United …
spreading around the world. Several SARS‐CoV‐2 endemic variants were found in United …
The role of cell death in SARS-CoV-2 infection
C Yuan, Z Ma, J **e, W Li, L Su, G Zhang, J Xu… - Signal transduction and …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), showing high
infectiousness, resulted in an ongoing pandemic termed coronavirus disease 2019 (COVID …
infectiousness, resulted in an ongoing pandemic termed coronavirus disease 2019 (COVID …