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How cortical circuits implement cortical computations: mouse visual cortex as a model
The mouse, as a model organism to study the brain, gives us unprecedented experimental
access to the mammalian cerebral cortex. By determining the cortex's cellular composition …
access to the mammalian cerebral cortex. By determining the cortex's cellular composition …
Inhibitory stabilization and cortical computation
Neuronal networks with strong recurrent connectivity provide the brain with a powerful
means to perform complex computational tasks. However, high-gain excitatory networks are …
means to perform complex computational tasks. However, high-gain excitatory networks are …
The influence of cortical activity on perception depends on behavioral state and sensory context
The mechanistic link between neural circuit activity and behavior remains unclear. While
manipulating cortical activity can bias certain behaviors and elicit artificial percepts, some …
manipulating cortical activity can bias certain behaviors and elicit artificial percepts, some …
The stabilized supralinear network: a unifying circuit motif underlying multi-input integration in sensory cortex
Neurons in sensory cortex integrate multiple influences to parse objects and support
perception. Across multiple cortical areas, integration is characterized by two neuronal …
perception. Across multiple cortical areas, integration is characterized by two neuronal …
[HTML][HTML] Optimal control of transient dynamics in balanced networks supports generation of complex movements
Populations of neurons in motor cortex engage in complex transient dynamics of large
amplitude during the execution of limb movements. Traditional network models with …
amplitude during the execution of limb movements. Traditional network models with …
Inhibition stabilization is a widespread property of cortical networks
Many cortical network models use recurrent coupling strong enough to require inhibition for
stabilization. Yet it has been experimentally unclear whether inhibition-stabilized network …
stabilization. Yet it has been experimentally unclear whether inhibition-stabilized network …
A disinhibitory circuit for contextual modulation in primary visual cortex
Context guides perception by influencing stimulus saliency. Accordingly, in visual cortex,
responses to a stimulus are modulated by context, the visual scene surrounding the …
responses to a stimulus are modulated by context, the visual scene surrounding the …
Cortical-like dynamics in recurrent circuits optimized for sampling-based probabilistic inference
Sensory cortices display a suite of ubiquitous dynamical features, such as ongoing noise
variability, transient overshoots and oscillations, that have so far escaped a common …
variability, transient overshoots and oscillations, that have so far escaped a common …
The dynamical regime of sensory cortex: stable dynamics around a single stimulus-tuned attractor account for patterns of noise variability
Correlated variability in cortical activity is ubiquitously quenched following stimulus onset, in
a stimulus-dependent manner. These modulations have been attributed to circuit dynamics …
a stimulus-dependent manner. These modulations have been attributed to circuit dynamics …
Flexible gating of contextual influences in natural vision
Identical sensory inputs can be perceived as markedly different when embedded in distinct
contexts. Neural responses to simple stimuli are also modulated by context, but the …
contexts. Neural responses to simple stimuli are also modulated by context, but the …