Dynamic responsiveness of self‐assembling peptide‐based nano‐drug systems

Y Wang, J Zhan, J Huang, X Wang… - Interdisciplinary …, 2023 - Wiley Online Library
Dynamic‐responsive self‐assembly is the process of ordered supramolecular structure
formation or reversible decomposition from building blocks. This process is driven by non …

Overcoming tumor microenvironment obstacles: current approaches for boosting nanodrug delivery

X Wang, H Zhang, X Chen, C Wu, K Ding, G Sun… - Acta Biomaterialia, 2023 - Elsevier
In order to achieve targeted delivery of anticancer drugs, efficacy improvement, and side
effect reduction, various types of nanoparticles are employed. However, their therapeutic …

In Situ Transformable Supramolecular Nanomedicine Targeted Activating Hippo Pathway for Triple-Negative Breast Cancer Growth and Metastasis Inhibition

Z Wang, C Yang, H Zhang, Y Gao, M **ao, Z Wang… - ACS …, 2022 - ACS Publications
As it is closely associated with tumor proliferation, metastasis, and the immunosuppressive
microenvironment, the dysfunctional Hippo pathway has become an extremely attractive …

Endogenous stimuli-responsive nanoparticles for cancer therapy: from bench to bedside

F **e, M Wang, Q Chen, T Chi, S Zhu, P Wei… - Pharmacological …, 2022 - Elsevier
Cancer is complicated to treat because of its high propensity for recurrence and metastasis,
and various side effects of conventional cancer treatments. With the development of …

Recent progress in nanocarrier-based drug delivery systems for antitumour metastasis

S Peng, X Yuan, H Li, Y Wei, B Zhou, G Ding… - European Journal of …, 2023 - Elsevier
Tumour metastasis is one of the major factors leading to poor prognosis as well as lower
survival among cancer patients. A number of studies investigating the inhibition of tumour …

Construction of size-transformable supramolecular nano-platform against drug-resistant colorectal cancer caused by Fusobacterium nucleatum

X Yan, F Ma, Q Chen, X Gou, X Li, L Zhang… - Chemical Engineering …, 2022 - Elsevier
The presence of Fusobacterium nucleatum (F. nucleatum) in the community of colorectal
cancer (CRC) accounts for its chemotherapy resistance. To resolve this drawback, we …

Molecular recognition of peptides and proteins by cucurbit [n] urils: systems and applications

L Armstrong, SL Chang, N Clements, Z Hirani… - Chemical Society …, 2024 - pubs.rsc.org
The development of methodology for attaching ligand binding sites to proteins of interest has
accelerated biomedical science. Such protein tags have widespread applications as well as …

In situ stimulus-responsive self-assembled nanomaterials for drug delivery and disease treatment

Z Yan, Y Liu, L Zhao, J Hu, Y Du, X Peng, Z Liu - Materials Horizons, 2023 - pubs.rsc.org
The individual motifs that respond to specific stimuli for the self-assembly of nanomaterials
play important roles. In situ constructed nanomaterials are formed spontaneously without …

[HTML][HTML] Mitochondrion-targeted supramolecular “nano-boat” simultaneously inhibiting dual energy metabolism for tumor selective and synergistic chemo-radiotherapy

J Gao, Z Wang, Q Guo, H Tang, Z Wang, C Yang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Tumor energy metabolism has been a well-appreciated target of cancer therapy;
however, the metabolism change of cancer cells between oxidative phosphorylation and …

Cucurbit [n] uril-based nanostructure construction and modification

L Mao, S Li, X Zhang, ZT Li, D Ma - Chinese Chemical Letters, 2024 - Elsevier
New fabrication method of nanostructures is of great importance for the applications of
nanoscience and nanotechnology. This review summarizes cucurbit [n] uril (CB [n])-based …