Key epigenetic enzymes modulated by natural compounds contributes to tumorigenicity
X Zhou, W Liu, Z Liang, J Liang, T Zhang, W Gao… - International Journal of …, 2025 - Elsevier
Dysregulation of epigenetic regulation is observed in numerous tumor cells. The therapeutic
effects of natural products on tumors were investigated through a comprehensive analysis of …
effects of natural products on tumors were investigated through a comprehensive analysis of …
ADAR Family Proteins: A Structural Review
This review aims to highlight the structures of ADAR proteins that have been crucial in the
discernment of their functions and are relevant to future therapeutic development. ADAR …
discernment of their functions and are relevant to future therapeutic development. ADAR …
Unveiling the gut microbiota blueprint of schizophrenia: a multilevel omics approach
DD Qi, P Liu, YM Wang, XG Tai, SF Ma - Frontiers in Psychiatry, 2024 - frontiersin.org
Background Schizophrenia is a persistent incurable mental disorder and is characterized by
the manifestation of negative emotions and behaviors with anxiety and depression, fear and …
the manifestation of negative emotions and behaviors with anxiety and depression, fear and …
[HTML][HTML] Design of Inhibitors That Target the Menin–Mixed-Lineage Leukemia Interaction
The prognosis of mixed-lineage leukemia (MLL) has remained a significant health concern,
especially for infants. The minimal treatments available for this aggressive type of leukemia …
especially for infants. The minimal treatments available for this aggressive type of leukemia …
[PDF][PDF] Role of Methylation in Regulation and Physiology of 5HT2C Gene in the Brain and Plausible Impact of Cys23ser Polymorphism: A Bioinformatics Approach
KKH Bhogegowda, S Niketh - 2024 - academia.edu
Signal transduction through G-proteins is a prominent feature of several eukaryotes. 5-HT2C
receptor, a G-protein-coupled receptor (GPCR), is a candidate of interest for the treatment of …
receptor, a G-protein-coupled receptor (GPCR), is a candidate of interest for the treatment of …
Development of a Computational Drug Discovery Pipeline for RNA Inhibitors: A Case Study with Targeting microRNA-21
KKJ Gunasinghe - 2024 - figshare.swinburne.edu.au
RNAs, particularly non-coding RNA types are known to be involved in several cancers
hijacking several cellular pathways. Drug discovery efforts in finding therapies against these …
hijacking several cellular pathways. Drug discovery efforts in finding therapies against these …