Growth factors play a crucial role in regulating a broad variety of biological processes and
are regarded as powerful therapeutic agents in tissue engineering and regenerative …

Successful regeneration of large segmental bone defects remains a major challenge in
clinical orthopedics, thus it is of important significance to fabricate a suitable alternative …

Despite tremendous advances in the field of regenerative medicine, it still remains
challenging to repair the osteochondral interface and full-thickness articular cartilage …

Bone morphogenetic protein-2 (BMP-2) is currently the only Food and Drug Administration
(FDA)-approved osteoinductive growth factor used as a bone graft substitute. However, with …

Shortcomings related to the treatment of bone diseases and consequent tissue regeneration
such as transplants have been addressed to some extent by tissue engineering and …

Electrospinning is well thought of as the most potent nanofiber producing technique, which
is applicable in biomedical fields. The generation of electrospun nanofibers as drug carriers …

Polymer membranes have been widely used in guided tissue regeneration (GTR) and
guided bone regeneration (GBR). In this review, various commercially available membranes …

Bone morphogenetic proteins (BMPs) are responsible for bone formation during
embryogenesis and bone regeneration and remodeling. The osteoinductive action of BMPs …

Titanium and its alloys are dominant material for orthopedic/dental implants due to their
stable chemical properties and good biocompatibility. However, aseptic loosening and peri …

Scaffolds functionalized with bone morphogenetic protein-2 (BMP-2) have shown great
potential for bone regeneration. However, structural instability and the necessity for supra …