Functional connectomics in depression: insights into therapies

Y Chai, YI Sheline, DJ Oathes, NL Balderston… - Trends in cognitive …, 2023 - cell.com
Depression is a common mental disorder characterized by heterogeneous cognitive and
behavioral symptoms. The emerging research paradigm of functional connectomics has …

The challenges and prospects of brain-based prediction of behaviour

J Wu, J Li, SB Eickhoff, D Scheinost… - Nature human …, 2023 - nature.com
Relating individual brain patterns to behaviour is fundamental in system neuroscience.
Recently, the predictive modelling approach has become increasingly popular, largely due …

[HTML][HTML] One size does not fit all: methodological considerations for brain-based predictive modeling in psychiatry

E Dhamala, BTT Yeo, AJ Holmes - Biological Psychiatry, 2023 - Elsevier
Psychiatric illnesses are heterogeneous in nature. No illness manifests in the same way
across individuals, and no two patients with a shared diagnosis exhibit identical symptom …

The burden of reliability: How measurement noise limits brain-behaviour predictions

M Gell, SB Eickhoff, A Omidvarnia, V Küppers, KR Patil… - BioRxiv, 2023 - biorxiv.org
Current major efforts in human neuroimaging research aim to understand individual
differences and identify biomarkers for clinical applications. One particularly promising …

Functional brain networks are associated with both sex and gender in children

E Dhamala, DS Bassett, BTT Yeo, AJ Holmes - Science Advances, 2024 - science.org
Sex and gender are associated with human behavior throughout the life span and across
health and disease, but whether they are associated with similar or distinct neural …

Generalizable and replicable brain-based predictions of cognitive functioning across common psychiatric illness

S Chopra, E Dhamala, C Lawhead, JA Ricard… - Science …, 2024 - science.org
A primary aim of computational psychiatry is to establish predictive models linking individual
differences in brain functioning with symptoms. In particular, cognitive impairments are …

[HTML][HTML] Relationship between prediction accuracy and feature importance reliability: An empirical and theoretical study

J Chen, LQR Ooi, TWK Tan, S Zhang, J Li, CL Asplund… - NeuroImage, 2023 - Elsevier
There is significant interest in using neuroimaging data to predict behavior. The predictive
models are often interpreted by the computation of feature importance, which quantifies the …

Latent profiles of childhood adversity, adolescent mental health, and neural network connectivity

FA Hardi, AM Beltz, V McLoyd… - JAMA Network …, 2024 - jamanetwork.com
Importance Adverse childhood experiences are pervasive and heterogeneous, with
potential lifelong consequences for psychiatric morbidity and brain health. Existing research …

[HTML][HTML] Comparison between gradients and parcellations for functional connectivity prediction of behavior

R Kong, YR Tan, N Wulan, LQR Ooi, SR Farahibozorg… - NeuroImage, 2023 - Elsevier
Resting-state functional connectivity (RSFC) is widely used to predict behavioral measures.
To predict behavioral measures, representing RSFC with parcellations and gradients are the …

A meta-analysis and systematic review of single vs. multimodal neuroimaging techniques in the classification of psychosis

A Porter, S Fei, KSF Damme, R Nusslock… - Molecular …, 2023 - nature.com
Background Psychotic disorders are characterized by structural and functional abnormalities
in brain networks. Neuroimaging techniques map and characterize such abnormalities using …