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Strategic approaches to improvise peptide drugs as next generation therapeutics
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …
RGD modified polymers: biomaterials for stimulated cell adhesion and beyond
U Hersel, C Dahmen, H Kessler - Biomaterials, 2003 - Elsevier
Since RGD peptides (R: arginine; G: glycine; D: aspartic acid) have been found to promote
cell adhesion in 1984 (Cell attachment activity of fibronectin can be duplicated by small …
cell adhesion in 1984 (Cell attachment activity of fibronectin can be duplicated by small …
Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine
The intestinal epithelial cells (IECs) constitute the primary barrier between host cells and
numerous foreign antigens; it is unclear how IECs induce the protective immunity against …
numerous foreign antigens; it is unclear how IECs induce the protective immunity against …
Caspase structure, proteolytic substrates, and function during apoptotic cell death
DW Nicholson - Cell Death & Differentiation, 1999 - nature.com
Caspases play an essential role during apoptotic cell death. These enzymes define a new
class of cysteine proteases and comprise a multi-gene family with more than a dozen distinct …
class of cysteine proteases and comprise a multi-gene family with more than a dozen distinct …
A decade of caspases
A Degterev, M Boyce, J Yuan - Oncogene, 2003 - nature.com
Caspases are a family of cysteine proteases that play important roles in regulating
apoptosis. A decade of research has generated a wealth of information on the signal …
apoptosis. A decade of research has generated a wealth of information on the signal …
Proteases for cell suicide: functions and regulation of caspases
Caspases are a large family of evolutionarily conserved proteases found from
Caenorhabditis elegans to humans. Although the first caspase was identified as a …
Caenorhabditis elegans to humans. Although the first caspase was identified as a …
Novel insights into the function and dynamics of extracellular matrix in liver fibrosis
Emerging evidence suggests that altered components and posttranslational modifications of
proteins in the extracellular matrix (ECM) may both initiate and drive disease progression …
proteins in the extracellular matrix (ECM) may both initiate and drive disease progression …
Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation
Angiogenesis, or the formation of new blood vessels out of pre-existing capillaries, is a
sequence of events that is fundamental to many physiologic and pathologic processes such …
sequence of events that is fundamental to many physiologic and pathologic processes such …
Tissue engineering: a new paradigm for periodontal regeneration based on molecular and cell biology.
PM Bartold, CAG Mcculloch… - Periodontology …, 2000 - search.ebscohost.com
Focuses on tissue engineering as paradigm for periodontal regeneration based on
molecular and cell biology. Reestablishment of soft tissue attachment on root surface; …
molecular and cell biology. Reestablishment of soft tissue attachment on root surface; …
Anticancer peptides mechanisms, simple and complex
P Norouzi, M Mirmohammadi, MHH Tehrani - Chemico-Biological …, 2022 - Elsevier
Peptide therapy has started since 1920s with the advent of insulin application, and now it
has emerged as a new approach in treatment of diseases including cancer. Using anti …
has emerged as a new approach in treatment of diseases including cancer. Using anti …