Gender-specific impact of sex hormones on the immune system

F Sciarra, F Campolo, E Franceschini… - International journal of …, 2023 - mdpi.com
Sex hormones are key determinants of gender-related differences and regulate growth and
development during puberty. They also exert a broad range modulation of immune cell …

Sex differences in differentiated thyroid cancer

L Shobab, KD Burman, L Wartofsky - Thyroid, 2022 - liebertpub.com
Background: Sex dimorphism strongly impacts tumor biology, with most cancers having a
male predominance. Uniquely, thyroid cancer (TC) is the only nonreproductive cancer with …

Testosterone affects type I/type II interferon response of neutrophils during hepatic amebiasis

M Er-Lukowiak, S Hänzelmann, M Rothe… - Frontiers in …, 2023 - frontiersin.org
Differences in immune response between men and women may influence the outcome of
infectious diseases. Intestinal infection with Entamoeba histolytica leads to hepatic …

[HTML][HTML] The similarities and differences between the effects of testosterone and DHEA on the innate and adaptive immune response

FO Buendía-González, M Legorreta-Herrera - Biomolecules, 2022 - mdpi.com
Androgens are steroids that modulate various processes in the body, ranging from
reproduction, metabolism, and even immune response. The main androgens are …

Haematological actions of androgens

AM Warren, M Grossmann - … Practice & Research Clinical Endocrinology & …, 2022 - Elsevier
In this review, we discuss the effects on androgens on the haemopoietic system, focussing
largely on the effects of testosterone on erythropoiesis. Stimulation of erythropoiesis is one …

[HTML][HTML] Sex steroids effects on asthma: a network perspective of immune and airway cells

NA Borkar, CK Combs, V Sathish - Cells, 2022 - mdpi.com
A multitude of evidence has suggested the differential incidence, prevalence and severity of
asthma between males and females. A compilation of recent literature recognized sex …

Influence of androgens on the innate immune system

S Vancolen, G Sébire, B Robaire - Andrology, 2023 - Wiley Online Library
Background Sexual dimorphism is observed in the occurrence, course, and severity of
human disease. The difference in immune response between males and females can in part …

Gender-diverse inclusion in immunological research: benefits to science and health

H Peckham, K Webb, EC Rosser, G Butler… - Frontiers in …, 2022 - frontiersin.org
The differences between male and female immune systems are an under-researched field,
ripe for discovery. This is evidenced by the stark sex biases seen in autoimmunity and …

Androgen exposure impairs neutrophil maturation and function within the infected kidney

TN Hreha, CA Collins, EB Cole, RJ **, DA Hunstad - Mbio, 2024 - journals.asm.org
Urinary tract infections (UTIs) in men are uncommon yet carry an increased risk for severe
pyelonephritis and other complications. In models of Escherichia coli UTI, C3H/HeN mice …

Testosterone exacerbates neutrophilia and cardiac injury in myocardial infarction via actions in bone marrow

E Svedlund Eriksson, M Lantero Rodriguez… - Nature …, 2025 - nature.com
Men develop larger infarct sizes than women after a myocardial infarction (MI), but the
mechanism underlying this sex difference is unknown. Here, we demonstrated that blood …