Pyrazolines and pyrazolones are prevalent cores in drugs and bioactive molecules.
Functionalizing them with heteroatoms on the ring improves or expands their clinical …

Breast cancer (BC) is a global health concern and the leading cause of cancerous death
among women across the world, BC has been characterized by fresh lump in the breast or …

In this study, we synthesized a number of new intriguing azoles bearing nicotinoyl moiety,
their antimicrobial and antitumor activities were investigated as well. We succeeded to …

The oxadiazole ring has long been used for the treatment of several diseases. This study
aimed to analyze the antihyperglycemic and antioxidant roles of the 1, 3, 4‐oxadiazole …

Purpose: Hyperlipidemia being the prominent risk factor of cardiovascular diseases and side
effects associated with the current lipid-lowering drugs have attracted the interest of …

A straightforward and high yielding synthetic approach is employed to synthesize the novel
1 H-1, 2, 3-triazole tethered pyrazolo [5, 1-b] quinazoline hybrids 7 (a–t) as new …

Thiazolidinedione derivatives represent nitrogen‐containing heterocyclic compounds
utilized in type 2 diabetes mellitus management. Recent advances in medicinal chemistry …

A copper-catalyzed oxidative annulation of sydnones with perfluorocarboxylic anhydride for
the synthesis of 3-aryl-5-fluoroalkyl-1, 3, 4-oxadiazol-2 (3 H)-ones is developed. A diverse …

Cancer is a common public health disease causing mortality worldwide. Thus, providing
novel chemotherapies that tackle breast cancer is of great interest. In this investigation …

A transition metal‐free method for the cycloisomerization of propargylic amides to oxazoles
was developed. The reaction utilizes in situ generated hydrogen chloride in …