Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions
P Lu, D Ruan, M Huang, M Tian, K Zhu… - Signal transduction and …, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …
Engineered hydrogels for mechanobiology
Cells' local mechanical environment can be as important in guiding cellular responses as
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …
[HTML][HTML] Biomaterials/bioinks and extrusion bioprinting
Bioinks are formulations of biomaterials and living cells, sometimes with growth factors or
other biomolecules, while extrusion bioprinting is an emerging technique to apply or deposit …
other biomolecules, while extrusion bioprinting is an emerging technique to apply or deposit …
[HTML][HTML] Extracellular matrix-derived materials for tissue engineering and regenerative medicine: a journey from isolation to characterization and application
Biomaterial choice is an essential step during the development tissue engineering and
regenerative medicine (TERM) applications. The selected biomaterial must present …
regenerative medicine (TERM) applications. The selected biomaterial must present …
3D printing of microenvironment‐specific bioinspired and exosome‐reinforced hydrogel scaffolds for efficient cartilage and subchondral bone regeneration
Q Li, H Yu, F Zhao, C Cao, T Wu, Y Fan… - Advanced …, 2023 - Wiley Online Library
In clinical practice, repairing osteochondral defects presents a challenge due to the varying
biological properties of articular cartilages and subchondral bones. Thus, elucidating how …
biological properties of articular cartilages and subchondral bones. Thus, elucidating how …
Cancer spheroids and organoids as novel tools for research and therapy: state of the art and challenges to guide precision medicine
S El Harane, B Zidi, N El Harane, KH Krause, T Matthes… - Cells, 2023 - mdpi.com
Spheroids and organoids are important novel players in medical and life science research.
They are gradually replacing two-dimensional (2D) cell cultures. Indeed, three-dimensional …
They are gradually replacing two-dimensional (2D) cell cultures. Indeed, three-dimensional …
Harnessing 3D in vitro systems to model immune responses to solid tumours: a step towards improving and creating personalized immunotherapies
In vitro 3D models are advanced biological tools that have been established to overcome
the shortcomings of oversimplified 2D cultures and mouse models. Various in vitro 3D …
the shortcomings of oversimplified 2D cultures and mouse models. Various in vitro 3D …
Preparation and use of decellularized extracellular matrix for tissue engineering
The multidisciplinary fields of tissue engineering and regenerative medicine have the
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …
A comprehensive review on 3D tissue models: biofabrication technologies and preclinical applications
R **e, V Pal, Y Yu, X Lu, M Gao, S Liang, M Huang… - Biomaterials, 2024 - Elsevier
The limitations of traditional two-dimensional (2D) cultures and animal testing, when it
comes to precisely foreseeing the toxicity and clinical effectiveness of potential drug …
comes to precisely foreseeing the toxicity and clinical effectiveness of potential drug …
Engineered organoids for biomedical applications
As miniaturized and simplified stem cell-derived 3D organ-like structures, organoids are
rapidly emerging as powerful tools for biomedical applications. With their potential for …
rapidly emerging as powerful tools for biomedical applications. With their potential for …