Despite two decades of intensified research to understand and cure tuberculosis disease,
biological uncertainties remain and hamper progress. However, owing to collaborative …

Isatin, chemically an indole-1 H-2, 3-dione, is recognised as one of the most attractive
therapeutic fragments in drug design and development. The template has turned out to be …

Abstract Bedaquiline (BDQ), a first-in-class diarylquinoline anti-tuberculosis drug, and its
analogue, TBAJ-587, prevent the growth and proliferation of Mycobacterium tuberculosis by …

We have developed an efficient gold-catalyzed C–O cross-coupling reaction of (hetero) aryl
iodides with primary and secondary alcohols via an AuI–AuIII catalytic cycle. This protocol …

Tuberculosis has remained a global concern for public health affecting the lives of people for
ages. Approximately 10 million people are affected by the disease and 1.5 million succumb …

Delamanid, bedaquiline, and pretomanid have been recently added in the anti-tuberculosis
(anti-TB) treatment regimens and have emerged as potential solutions for combating drug …

Tuberculosis (TB), characterized by high mortality and low diagnosis, is caused by a single
pathogen, Mycobacterium tuberculosis (Mtb). Imaging tools that can be used to track Mtb …

One of the biggest health challenges of today's world is the emergence of antimicrobial
resistance (AMR), which renders conventional therapeutics insufficient and urgently …

Tuberculosis (TB) remains one of the deadliest infectious diseases caused by
Mycobacterium tuberculosis (M. tb). It is responsible for significant causes of mortality and …

The discovery of new antimicrobial agents as a means of treating drug-resistant microbial
pathogens is of utmost significance to overcome their immense risk to human well-being …