Effect of Clostridium butyricum on Gastrointestinal Infections

T Ariyoshi, M Hagihara, M Takahashi, H Mikamo - Biomedicines, 2022 - mdpi.com
Clostridium butyricum is a human commensal bacterium with beneficial effects including
butyrate production, spore formation, increasing levels of beneficial bacteria, and inhibition …

[HTML][HTML] Clostridium difficile infection: a review of current and emerging therapies

A Ofosu - Annals of gastroenterology: quarterly publication of the …, 2016 - ncbi.nlm.nih.gov
Clostridium difficile (C. difficile) infection (CDI) is the most common cause of healthcare-
associated infections in US hospitals. The epidemic strain NAP1/BI/ribotype 027 accounts …

Frizzled proteins are colonic epithelial receptors for C. difficile toxin B

L Tao, J Zhang, P Meraner, A Tovaglieri, X Wu… - Nature, 2016 - nature.com
Clostridium difficile toxin B (TcdB) is a critical virulence factor that causes diseases
associated with C. difficile infection. Here we carried out CRISPR–Cas9-mediated genome …

TFPI is a colonic crypt receptor for TcdB from hypervirulent clade 2 C. difficile

J Luo, Q Yang, X Zhang, Y Zhang, L Wan, X Zhan… - Cell, 2022 - cell.com
The emergence of hypervirulent clade 2 Clostridioides difficile is associated with severe
symptoms and accounts for> 20% of global infections. TcdB is a dominant virulence factor of …

Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B

P Chen, L Tao, T Wang, J Zhang, A He, K Lam, Z Liu… - Science, 2018 - science.org
Clostridium difficile infection is the most common cause of antibiotic-associated diarrhea in
developed countries. The major virulence factor, C. difficile toxin B (TcdB), targets colonic …

The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection

X Sun, SA Hirota - Molecular immunology, 2015 - Elsevier
Clostridium difficile (C. difficile) is the most common cause of nosocomial antibiotic-
associated diarrhea and the etiologic agent of pseudomembranous colitis. The clinical …

Clostridioides difficile Toxin B Induced Senescence: A New Pathologic Player for Colorectal Cancer?

K Fettucciari, A Fruganti, F Stracci, A Spaterna… - International Journal of …, 2023 - mdpi.com
Clostridioides difficile (C. difficile) is responsible for a high percentage of gastrointestinal
infections and its pathological activity is due to toxins A and BC difficile infection (CDI) is …

Structure of the glucosyltransferase domain of TcdA in complex with RhoA provides insights into substrate recognition

B Chen, Z Liu, K Perry, R ** - Scientific reports, 2022 - nature.com
Clostridioides difficile is one of the most common causes of antibiotic-associated diarrhea in
developed countries. As key virulence factors of C. difficile, toxin A (TcdA) and toxin B (TcdB) …

Clostridium difficile in foods and animals: history and measures to reduce exposure

A Rodriguez-Palacios, S Borgmann… - Animal health …, 2013 - cambridge.org
Many articles have summarized the changing epidemiology of Clostridium difficile infections
(CDI) in humans, but the emerging presence of C. difficile in foods and animals and possible …

Рекомендации Российской гастроэнтерологической ассоциации по диагностике и лечению желчнокаменной болезни

ВТ Ивашкин, ИВ Маев, ЕК Баранская… - Ремедиум …, 2016 - cyberleninka.ru
ЖКБ может протекать бессимптомно. Клинические проявления возникают при развитии
воспаления или обструкции желчных путей при миграции камней в область шейки …