Despite the many advances that have occurred in the field of vaccine adjuvants, there are
still unmet needs that may enable the development of vaccines suitable for more …

Introduction The development of an effective vaccine to protect against HIV is a longstanding
global health need complicated by challenges inherent to HIV biology and to the execution …

Introduction: From its earliest days, the US. military has embraced the use of vaccines to fight
infectious diseases. The Army Liposome Formulation (ALF) has been a pivotal innovation as …

Introduction Liposomes have been used as carriers for vaccine adjuvants and antigens due
to their inherent biocompatibility and versatility as delivery vehicles. Two vial admixture of …

The advances in the development of drugs and vaccines for major infectious diseases of
tuberculosis (TB), malaria and HIV represent some of the most significant milestones in their …

To augment HIV-1 pox-protein vaccine immunogenicity using a next generation adjuvant, a
prime-boost strategy of recombinant modified vaccinia virus Ankara and multimeric Env …

Protection from human immunodeficiency virus (HIV) acquisition will likely require an
effective vaccine that elicits antibodies against the HIV‐1 envelope glycoproteins (Envs) …

A major barrier in the use of humanized mice as models of HIV-1 (HIV) infection is the
inadequate generation of virus-specific antibody responses. Humanized DRAGA (hDRAGA) …

Background: Leishmaniases are neglected diseases caused by infection with Leishmania
parasites and there are no human vaccines in use routinely. The purpose of this study was …

Infection is the predominant cause of mortality in early life, and immunization is the most
promising biomedical intervention to reduce this burden. However, very young infants fail to …