The ménage à trois of autophagy, lipid droplets and liver disease

Y Filali-Mouncef, C Hunter, F Roccio, S Zagkou… - Autophagy, 2022 - Taylor & Francis
Autophagic pathways cross with lipid homeostasis and thus provide energy and essential
building blocks that are indispensable for liver functions. Energy deficiencies are …

Reactive oxygen species and cancer paradox: To promote or to suppress?

S Galadari, A Rahman, S Pallichankandy… - Free Radical Biology …, 2017 - Elsevier
Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

Alkaloids for cancer prevention and therapy: Current progress and future perspectives

A Mondal, A Gandhi, C Fimognari, AG Atanasov… - European journal of …, 2019 - Elsevier
Alkaloids are important chemical compounds that serve as a rich source for drug discovery.
Numerous alkaloids screened from medicinal plants and herbs showed antiproliferative and …

Induction of reactive oxygen species: an emerging approach for cancer therapy

Z Zou, H Chang, H Li, S Wang - Apoptosis, 2017 - Springer
Reactive oxygen species (ROS), a group of ions and molecules, include hydroxyl radicals (·
OH), alkoxyl radicals, superoxide anion (O 2·−), singlet oxygen (1 O 2) and hydrogen …

Mitochondrial dynamics, ROS, and cell signaling: a blended overview

V Brillo, L Chieregato, L Leanza, S Muccioli, R Costa - Life, 2021 - mdpi.com
Mitochondria are key intracellular organelles involved not only in the metabolic state of the
cell, but also in several cellular functions, such as proliferation, Calcium signaling, and lipid …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

[HTML][HTML] Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids

AQ Khan, K Rashid, AA AlAmodi, MV Agha… - Biomedicine & …, 2021 - Elsevier
Reactive oxygen species play crucial role in biological homeostasis and pathogenesis of
human diseases including cancer. In this line, now it has become evident that ROS …

[HTML][HTML] Guidelines for the use and interpretation of assays for monitoring autophagy 1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah… - …, 2021 - pmc.ncbi.nlm.nih.gov
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

[HTML][HTML] Bioactivity and mechanism of action of sanguinarine and its derivatives in the past 10 years

LJ Huang, JX Lan, JH Wang, H Huang, K Lu… - Biomedicine & …, 2024 - Elsevier
Sanguinarine is a quaternary ammonium benzophenanthine alkaloid found in traditional
herbs such as Chelidonium, Corydalis, Sanguinarum, and Borovula. It has been proven to …

Natural products to prevent drug resistance in cancer chemotherapy: a review

R Yuan, Y Hou, W Sun, J Yu, X Liu… - Annals of the new …, 2017 - Wiley Online Library
Chemotherapy is the standard internal medical treatment for cancer. However, the
resistance of cancer cells to nearly all kinds of chemotherapeutic drugs and targeted drugs …