Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

N 6-Methyladenosine (m 6 A), the most prevalent internal modification associated with
eukaryotic mRNAs, influences many steps of mRNA metabolism, including splicing, export …

Simple Summary Researchers have spent nearly two decades unraveling the roles of non-
coding RNAs in cancer biology. In recent years, deep transcriptomic profiling of tissue and …

Genome-editing technologies, in particular, CRISPR systems, are widely used for targeted
regulation of gene expression and obtaining modified human and animal cell lines, plants …

Mitochondria are dynamic organelles managing crucial processes of cellular metabolism
and bioenergetics. Enabling rapid cellular adaptation to altered endogenous and …

RNA modifications are diverse post-transcriptional modifications that regulate RNA
metabolism and gene expression. RNA modifications, and the writers, erasers, and readers …

Osteoporosis is a metabolic skeletal disorder in which bone mass is depleted and bone
structure is destroyed to the degree that bone becomes fragile and prone to fractures …

Epigenetic research involves examining the mitotically heritable processes that regulate
gene expression, independent of changes in the DNA sequence. Recent technical …

In human beings, there is a∼ 16,569 bp circular mitochondrial DNA (mtDNA) encoding 22
tRNAs, 12S and 16S rRNAs, 13 polypeptides that constitute the central core of ETC/OxPhos …

Our understanding of the expanded genetic alphabet has been growing rapidly over the last
two decades, and many of these developments came more than 80 years after the original …