Healthy articular cartilage, covering the ends of bones in major joints such as hips and
knees, presents the most efficiently‐lubricated surface known in nature, with friction …

Tissue engineering often uses synthetic scaffolds to direct cell responses during engineered
tissue development. Since cells reside within specific niches of the extracellular matrix, it is …

Adipose tissue (AT) expansion in obesity is characterized by cellular growth and continuous
extracellular matrix (ECM) remodeling with increased fibrillar collagen deposition. It is …

Advancements in coherent Raman scattering (CRS) microscopy have enabled label-free
visualization and analysis of functional, endogenous biomolecules in living systems. When …

The complex network structure of elastin and collagen extracellular matrix (ECM) forms the
primary load bearing components in the arterial wall. The structural and mechanobiological …

Tissue architecture is intimately linked with its functions, and loss of tissue organization is
often associated with pathologies. The intricate depth-dependent extracellular matrix (ECM) …

Advances in vibrational spectroscopy have propelled new insights into the molecular
composition and structure of biological tissues. In this review, we discuss common …

Raman spectroscopy is an analytical method based on light–matter interactions that can
interrogate the vibrational modes of matter and provide representative molecular …

Elastin is a major component of tissues such as lung and blood vessels, and endows them
with the long-range elasticity necessary for their physiological functions. Recent research …

Raman map** in combination with uni-and multi-variate methods of data analysis is
applied to articular cartilage samples. Main differences in biochemical composition and …