Epilepsy is a chronic neurologic disorder that affects over 70 million people worldwide.
Despite the availability of over 20 antiseizure drugs (ASDs) for symptomatic treatment of …

Coffee is one of the most widely consumed beverages worldwide. It is usually identified as a
stimulant because of a high content of caffeine. However, caffeine is not the only coffee …

Several neurodevelopmental and neuropsychiatric disorders are characterized by
intermittent episodes of pathological activity. Although genetic therapies offer the ability to …

The recent development of spatial omics methods has enabled single-cell profiling of the
transcriptome and 3D genome organization with high spatial resolution. Expanding the …

Radial glial (RG) development is essential for cerebral cortex growth and organization. In
humans, the outer radial glia (oRG) subtype is expanded and gives rise to diverse neurons …

Epilepsy is one of the most common and disabling neurologic conditions, yet we have an
incomplete understanding of the detailed pathophysiology and, thus, treatment rationale for …

The brain must dynamically integrate, coordinate, and respond to internal and external
stimuli across multiple time scales. Non-invasive measurements of brain activity with fMRI …

Abstract gamma-Aminobutyric acid (GABA)-mediated inhibitory neurotransmission and the
gene products involved were discovered during the mid-twentieth century. Historically …

Epilepsy is a common and serious neurologic disease with a strong genetic component.
Genetic studies have identified an increasing collection of disease-causing genes. The …

Hippocampal sclerosis (HS) is a common pathology encountered in mesial temporal lobe
epilepsy (MTLE) as well as other epilepsy syndromes and in both surgical and post‐mortem …