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[HTML][HTML] Engineered M13 phage as a novel therapeutic bionanomaterial for clinical applications: From tissue regeneration to cancer therapy
C Chang, W Guo, X Yu, C Guo, N Zhou, X Guo… - Materials Today Bio, 2023 - Elsevier
Bacteriophages (phages) are nanostructured viruses with highly selective antibacterial
properties that have gained attention beyond eliminating bacteria. Specifically, M13 phages …
properties that have gained attention beyond eliminating bacteria. Specifically, M13 phages …
Bioengineered human skeletal muscle capable of functional regeneration
Abstract Background Skeletal muscle (SkM) regenerates following injury, replacing
damaged tissue with high fidelity. However, in serious injuries, non-regenerative defects …
damaged tissue with high fidelity. However, in serious injuries, non-regenerative defects …
Ginkgolide B facilitates muscle regeneration via rejuvenating osteocalcin‐mediated bone‐to‐muscle modulation in aged mice
BYH Wang, YF Chen, AWT Hsiao… - Journal of Cachexia …, 2023 - Wiley Online Library
Background The progressive deterioration of tissue–tissue crosstalk with aging causes a
striking impairment of tissue homeostasis and functionality, particularly in the …
striking impairment of tissue homeostasis and functionality, particularly in the …
Bioengineered model of the human motor unit with physiologically functional neuromuscular junctions
Investigations of the human neuromuscular junction (NMJ) have predominately utilised
experimental animals, model organisms, or monolayer cell cultures that fail to represent the …
experimental animals, model organisms, or monolayer cell cultures that fail to represent the …
[HTML][HTML] Topography-mediated myotube and endothelial alignment, differentiation, and extracellular matrix organization for skeletal muscle engineering
AM Almonacid Suarez, MGL Brinker, LA Brouwer… - Polymers, 2020 - mdpi.com
Understanding the response of endothelial cells to aligned myotubes is important to create
an appropriate environment for tissue-engineered vascularized skeletal muscle. Part of the …
an appropriate environment for tissue-engineered vascularized skeletal muscle. Part of the …
Spatiotemporal single-cell tracking analysis in 3D tissues to reveal heterogeneous cellular response to mechanical stimuli
Mechanical stimuli have been recognized as important for tissue maturation, homeostasis
and constructing engineered three-dimensional (3D) tissues. However, we know little about …
and constructing engineered three-dimensional (3D) tissues. However, we know little about …
Modelling Skeletal Muscle Ageing and Repair In Vitro
J Tarum, H Degens, MD Turner… - Journal of Tissue …, 2023 - Wiley Online Library
Healthy skeletal muscle can regenerate after ischaemic, mechanical, or toxin‐induced
injury, but ageing impairs that regeneration potential. This has been largely attributed to …
injury, but ageing impairs that regeneration potential. This has been largely attributed to …
A concise in vitro model for evaluating interactions between macrophage and skeletal muscle cells during muscle regeneration
N Kase, Y Kitagawa, A Ikenaka, A Niwa… - Frontiers in Cell and …, 2023 - frontiersin.org
Skeletal muscle has a highly regenerative capacity, but the detailed process is not fully
understood. Several in vitro skeletal muscle regeneration models have been developed to …
understood. Several in vitro skeletal muscle regeneration models have been developed to …
Critical-Size Defect Tibialis Anterior (TA) Muscle Regeneration using Ex-Vivo Mice Hindlimbs Culturing under Dynamic Mechanical Loading
In this study, we introduced an innovative computer-controlled ex vivo mice hindlimb
culturing platform operating under dynamic loading, coupled with injectable cell-laden …
culturing platform operating under dynamic loading, coupled with injectable cell-laden …
Development of Skeletal Muscle Models to Study Ageing and Associated Conditions
J Tarum - 2023 - search.proquest.com
Rapid ageing of the population together with raised prevalence of chronic metabolic
diseases provokes huge economic burden on healthcare systems. Furthermore, age-related …
diseases provokes huge economic burden on healthcare systems. Furthermore, age-related …