Magnetization transfer contrast and chemical exchange saturation transfer MRI. Features and analysis of the field-dependent saturation spectrum

PCM Van Zijl, WW Lam, J Xu, L Knutsson, GJ Stanisz - Neuroimage, 2018 - Elsevier
Abstract Magnetization Transfer Contrast (MTC) and Chemical Exchange Saturation
Transfer (CEST) experiments measure the transfer of magnetization from molecular protons …

Clinical applications of chemical exchange saturation transfer (CEST) MRI

KM Jones, AC Pollard, MD Pagel - Journal of Magnetic …, 2018 - Wiley Online Library
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) has
been developed and employed in multiple clinical imaging research centers worldwide …

An overview of CEST MRI for non-MR physicists

B Wu, G Warnock, M Zaiss, C Lin, M Chen, Z Zhou… - EJNMMI physics, 2016 - Springer
The search for novel image contrasts has been a major driving force in the magnetic
resonance (MR) research community, in order to gain further information on the body's …

Glutamate imaging (GluCEST) lateralizes epileptic foci in nonlesional temporal lobe epilepsy

KA Davis, RPR Nanga, S Das, SH Chen… - Science translational …, 2015 - science.org
When neuroimaging reveals a brain lesion, drug-resistant epilepsy patients show better
outcomes after resective surgery than do the one-third of drug-resistant epilepsy patients …

Radiation toxicity in the central nervous system: mechanisms and strategies for injury reduction

DD Smart - Seminars in radiation oncology, 2017 - Elsevier
The potential for radiation-induced toxicities in the brain produces significant anxiety, both
among patients receiving radiation therapy and those radiation oncologists providing …

Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities

R Macrez, PK Stys, D Vivien, SA Lipton… - The Lancet …, 2016 - thelancet.com
Research advances support the idea that excessive activation of the glutamatergic pathway
plays an important part in the pathophysiology of multiple sclerosis. Beyond the well …

pH-weighted molecular imaging of gliomas using amine chemical exchange saturation transfer MRI

RJ Harris, TF Cloughesy, LM Liau, RM Prins… - Neuro …, 2015 - academic.oup.com
Background Interstitial tissue acidosis resulting from abnormal perfusion and metabolism is
a hallmark of cancer. The current study demonstrates that chemical exchange saturation …

A meta-analysis of ultra-high field glutamate, glutamine, GABA and glutathione 1HMRS in psychosis: Implications for studies of psychosis risk

VJ Sydnor, DR Roalf - Schizophrenia research, 2020 - Elsevier
Ultra-high field proton magnetic resonance spectroscopy (1 HMRS) offers a unique
opportunity to measure the concentration of neurometabolites implicated in psychosis (PSY) …

Spinal cord MRI at 7T

RL Barry, SJ Vannesjo, JC Gore, SA Smith - Neuroimage, 2018 - Elsevier
Magnetic resonance imaging (MRI) of the human spinal cord at 7T has been demonstrated
by a handful of research sites worldwide, and the spinal cord remains one of the areas in …

Glutamate imaging (GluCEST) reveals lower brain GluCEST contrast in patients on the psychosis spectrum

DR Roalf, RPR Nanga, PE Rupert, H Hariharan… - Molecular …, 2017 - nature.com
Psychosis commonly develops in adolescence or early adulthood. Youths at clinical high
risk (CHR) for psychosis exhibit similar, subtle symptoms to those with schizophrenia (SZ) …