Bioinformatics methods for mass spectrometry-based proteomics data analysis
Recent advances in mass spectrometry (MS)-based proteomics have enabled tremendous
progress in the understanding of cellular mechanisms, disease progression, and the …
progress in the understanding of cellular mechanisms, disease progression, and the …
Quantitative proteomics using isobaric labeling: a practical guide
X Chen, Y Sun, T Zhang, L Shu… - Genomics …, 2021 - academic.oup.com
In the past decade, relative proteomic quantification using isobaric labeling technology has
developed into a key tool for comparing the expression of proteins in biological samples …
developed into a key tool for comparing the expression of proteins in biological samples …
Extracting accurate precursor information for tandem mass spectra by RawConverter
Extraction of data from the proprietary RAW files generated by Thermo Fisher mass
spectrometers is the primary step for subsequent data analysis. High resolution and high …
spectrometers is the primary step for subsequent data analysis. High resolution and high …
Trapped ion mobility spectrometry reduces spectral complexity in mass spectrometry-based proteomics
In bottom-up mass spectrometry-based proteomics, deep proteome coverage is limited by
high cofragmentation rates. Cofragmentation occurs when more than one analyte is isolated …
high cofragmentation rates. Cofragmentation occurs when more than one analyte is isolated …
Chemical isotope labeling for quantitative proteomics
Advancements in liquid chromatography and mass spectrometry over the last decades have
led to a significant development in mass spectrometry‐based proteome quantification …
led to a significant development in mass spectrometry‐based proteome quantification …
Protein-induced pluripotent stem cells ameliorate cognitive dysfunction and reduce Aβ deposition in a mouse model of Alzheimer's disease
Transplantation of stem cells into the brain attenuates functional deficits in the central
nervous system via cell replacement, the release of specific neurotransmitters, and the …
nervous system via cell replacement, the release of specific neurotransmitters, and the …
Complementary proteomic approaches reveal mitochondrial dysfunction, immune and inflammatory dysregulation in a mouse model of Gulf War Illness
Z Zakirova, J Reed, G Crynen, L Horne… - PROTEOMICS …, 2017 - Wiley Online Library
Purpose Long‐term consequences of combined pyridostigmine bromide (PB) and
permethrin (PER) exposure in C57BL6/J mice using a well‐characterized mouse model of …
permethrin (PER) exposure in C57BL6/J mice using a well‐characterized mouse model of …
Removal of interference MS/MS spectra for accurate quantification in isobaric tag-based proteomics
M Iwasaki, T Tabata, Y Kawahara… - Journal of proteome …, 2019 - ACS Publications
Rapid progress in mass spectrometry (MS) has made comprehensive analyses of the
proteome possible, but accurate quantification remains challenging. Isobaric tags for relative …
proteome possible, but accurate quantification remains challenging. Isobaric tags for relative …
Advances and applications of stable isotope labeling-based methods for proteome relative quantitation
Proteins carry out numerous biological functions in living cells and form a dynamic system
under various physiological and pathological conditions. Advances in proteome quantitation …
under various physiological and pathological conditions. Advances in proteome quantitation …
Multiplexed Post-Experimental Monoisotopic Mass Refinement (mPE-MMR) to Increase Sensitivity and Accuracy in Peptide Identifications from Tandem Mass Spectra …
Mass spectrometry (MS)-based proteomics, which uses high-resolution hybrid mass
spectrometers such as the quadrupole-orbitrap mass spectrometer, can yield tens of …
spectrometers such as the quadrupole-orbitrap mass spectrometer, can yield tens of …