Gastric cancer remains a major unmet clinical problem with over 1 million new cases
worldwide. It is the fourth most commonly occurring cancer in men and the seventh most …

Background & Aims In 2017, the World Health Organization (WHO) designated
clarithromycin-resistant Helicobacter pylori a high priority for antibiotic research and …

Important progress has been made in the management of Helicobacter pylori infection and
in this fifth edition of the Maastricht Consensus Report, key aspects related to the clinical role …

Helicobacter pylori (H. pylori) infection is a common worldwide infection that is an important
cause of peptic ulcer disease and gastric cancer. H. pylorimay also have a role in …

Objective A global consensus meeting was held to review current evidence and knowledge
gaps and propose collaborative studies on population-wide screening and eradication of …

Following cancer, cells in a particular tissue can no longer respond to the factors involved in
controlling cell survival, differentiation, proliferation, and death. In recent years, it has been …

The commensal microbiota has been implicated in the regulation of a diverse array of
physiological processes, both within the gastrointestinal tract and at distant tissue sites …

Globally, gastrointestinal cancers represent more than one-fourth of all cancer incidence
and one-third of cancer-related mortality. Although there has been much progress in …

Background Patients with early gastric cancers that are limited to gastric mucosa or
submucosa usually have an advanced loss of mucosal glandular tissue (glandular atrophy) …

Gastric adenocarcinoma carries a poor prognosis, in part due to the late stage of diagnosis.
Risk factors include Helicobacter pylori infection, family history of gastric cancer—in …