Oral anticoagulant therapy: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians evidence-based clinical practice guidelines
Background The objective of this article is to summarize the published literature concerning
the pharmacokinetics and pharmacodynamics of oral anticoagulant drugs that are currently …
the pharmacokinetics and pharmacodynamics of oral anticoagulant drugs that are currently …
Coagulation testing in the core laboratory
WE Winter, SD Flax, NS Harris - Laboratory medicine, 2017 - academic.oup.com
Primary hemostasis begins with endothelial injury. VWF, produced by endothelial cells,
binds to platelets and links them to subendothelial collagen. Platelet-derived ADP and …
binds to platelets and links them to subendothelial collagen. Platelet-derived ADP and …
Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians evidence-based clinical practice guidelines
This article concerning the pharmacokinetics and pharmacodynamics of vitamin K
antagonists (VKAs) is part of the American College of Chest Physicians Evidence-Based …
antagonists (VKAs) is part of the American College of Chest Physicians Evidence-Based …
American Heart Association/American College of Cardiology foundation guide to warfarin therapy
rin. 25, 26 Inhibition of S-warfarin metabolism is more important clinically because this
isomer is 5 times more potent than the R-isomer as a vitamin K antagonist. 25, 26 …
isomer is 5 times more potent than the R-isomer as a vitamin K antagonist. 25, 26 …
Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range
Abbreviations: AFASAK Atrial Fibrillation, Aspirin, Anticoagulation; AMI acute myocardial
infarction; AF atrial fibrillation; CARS Coumadin Aspirin Reinfarction Study; CI confidence …
infarction; AF atrial fibrillation; CARS Coumadin Aspirin Reinfarction Study; CI confidence …
The pharmacology and management of the vitamin K antagonists: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
This article concerning the pharmacokinetics and pharmacodynamics of vitamin K
antagonists (VKAs) is part of the Seventh American College of Chest Physicians Conference …
antagonists (VKAs) is part of the Seventh American College of Chest Physicians Conference …
Standardization of prothrombin time/international normalized ratio (PT/INR)
The prothrombin time (PT) represents the most commonly used coagulation test in clinical
laboratories. The PT is mathematically converted to the international normalized ratio (INR) …
laboratories. The PT is mathematically converted to the international normalized ratio (INR) …
Vitamin K antagonists in heart disease: Current status and perspectives (Section III)
Oral anticoagulants are a mainstay of cardiovascular therapy, and for over 60 years vitamin
K antagonists (VKAs) were the only available agents for long-term use. VKAs interfere with …
K antagonists (VKAs) were the only available agents for long-term use. VKAs interfere with …
Embolic potential, prevention and management of mural thrombus complicating anterior myocardial infarction: a meta-analysis
PT Vaitkus, ES Barnathan - Journal of the American College of Cardiology, 1993 - Elsevier
Objective. The management of mural thrombus complicating acute anterior myocardial
infarction remains controversial in part because of the small size of studies on this topic. We …
infarction remains controversial in part because of the small size of studies on this topic. We …
Erratum to: pharmacology of anticoagulants used in the treatment of venous thromboembolism
Anticoagulant drugs are the foundation of therapy for patients with VTE. While effective
therapeutic agents, anticoagulants can also result in hemorrhage and other side effects …
therapeutic agents, anticoagulants can also result in hemorrhage and other side effects …