The polyadenosine RNA binding protein polyadenylate‐binding nuclear protein 1 (PABPN
1) plays key roles in post‐transcriptional processing of RNA. Although PABPN 1 is …

Poly (A) RNA‐binding proteins (Pabs) bind with high affinity and specificity to polyadenosine
RNA. Textbook models show a nuclear Pab, PABPN1, and a cytoplasmic Pab, PABPC …

The choice for a polyadenylation site determines the length of the 3′-untranslated region
(3′-UTRs) of an mRNA. Inclusion or exclusion of regulatory sequences in the 3′-UTR may …

Oculopharyngeal muscular dystrophy (OPMD) is a late-onset disorder characterized by
progressive weakness and degeneration of specific muscles. OPMD is due to extension of a …

The poly (A)-binding protein nuclear 1 is encoded by the PABPN1 gene, whose mutations
result in oculopharyngeal muscular dystrophy, a late-onset disorder for which the molecular …

Alternative polyadenylation (APA) is a molecular mechanism during a pre‐mRNA
processing that involves usage of more than one polyadenylation site (PA‐site) generating …

Oculopharyngeal muscular dystrophy (OPMD), a late-onset disorder characterized by
progressive degeneration of specific muscles, results from the extension of a polyalanine …

Oculopharyngeal muscular dystrophy (OPMD) is a late onset disease caused by polyalanine
expansion in the poly (A) binding protein nuclear 1 (PABPN1). Several mouse models have …

Ubiquitin‐binding domains (UBDs) are modular units found within ubiquitin‐binding proteins
that mediate the non‐covalent recognition of (poly) ubiquitin modifications. A variety of …

Oculopharyngeal muscular dystrophy (OPMD) is caused by trinucleotide repeat expansion
mutations in Poly (A) binding protein 1 (PABPN1). PABPN1 is a regulator of mRNA stability …