Computationally designed multi-subunit assemblies have shown considerable promise for a
variety of applications, including a new generation of potent vaccines. One of the major …

Introduction With the flood of engineered antibodies, there is a heightened need to elucidate
the structural features of antibodies that contribute to specificity, stability, and breadth. While …

Four, eight or twenty C3 symmetric protein trimers can be arranged with tetrahedral (T-sym),
octahedral (O-sym) or icosahedral (I-sym) point group symmetry to generate closed cage …

A wooden house frame consists of many different lumber pieces, but because of the
regularity of these building blocks, the structure can be designed using straightforward …

Molecular Dynamics (MD) simulations have been extensively employed to investigate
protein dynamics. In this context, MD simulations aim to understand intra-and inter …