Resistance of important bacterial pathogens to common antimicrobial therapies and the
emergence of multidrug-resistant bacteria are increasing at an alarming rate and constitute …

Covering: 2018 to 2022 Antimicrobial resistance (AMR) poses a significant global health
threat. There is a rising demand for innovative drug scaffolds and new targets to combat …

Antibiotic discovery is in crisis. Despite a growing need for new drugs resulting from the
increasing number of multi-antibiotic-resistant pathogens, there have been only a handful of …

Infections with Pseudomonas aeruginosa have become a concerning threat in hospital-
acquired infections and for cystic fibrosis patients. The major problem leading to high …

Resveratrol is a polyphenolic antioxidant whose possible health benefits include
anticarcinogenic, antiaging, and antimicrobial properties that have gained significant …

Due to the continued emergence of resistance and a lack of new and promising antibiotics,
bacterial infection has become a major public threat. High-throughput screening (HTS) …

The escalating emergence of resistant bacterial strains is one of the most important threats
to human health. With the increasing incidence of multi-drugs infections, there is an urgent …

The injectisome type three secretion system (T3SS) is a major virulence factor in
Pseudomonas aeruginosa. This bacterium is responsible for severe infections in …

For millennia, humanity has relied on plants for its medicines, and modern pharmacology
continues to reexamine and mine plant metabolites for novel compounds and to guide …

Antibiotic resistance is a global threat that should be urgently resolved. Finding a new
antibiotic is one way, whereas the repression of the dissemination of virulent pathogenic …