Idiopathic nephrotic syndrome in children
The incidence of idiopathic nephrotic syndrome (NS) is 1· 15–16· 9 per 100 000 children,
varying by ethnicity and region. The cause remains unknown but the pathogenesis of …
varying by ethnicity and region. The cause remains unknown but the pathogenesis of …
Nephrotic syndrome in infants and children: pathophysiology and management
Nephrotic syndrome is defined by nephrotic-range proteinuria (≥ 40 mg/m2/hour or urine
protein/creatinine ratio≥ 200 mg/mL or 3+ protein on urine dipstick), hypoalbuminaemia (< …
protein/creatinine ratio≥ 200 mg/mL or 3+ protein on urine dipstick), hypoalbuminaemia (< …
Steroid sensitive nephrotic syndrome: revised guidelines
Objective: To frame revised guidelines on diagnosis, evaluation, management, and
supportive care of patients with the illness. Process: The guidelines combine evidence …
supportive care of patients with the illness. Process: The guidelines combine evidence …
Efficacy of rituximab vs tacrolimus in pediatric corticosteroid-dependent nephrotic syndrome: a randomized clinical trial
B Basu, A Sander, B Roy, S Preussler, S Barua… - JAMA …, 2018 - jamanetwork.com
Importance Calcineurin inhibitors are an established first-line corticosteroid-sparing therapy
for patients with corticosteroid-dependent nephrotic syndrome (CDNS), whereas B …
for patients with corticosteroid-dependent nephrotic syndrome (CDNS), whereas B …
Incidence and relapse of idiopathic nephrotic syndrome: meta-analysis
F Veltkamp, LR Rensma, AHM Bouts - Pediatrics, 2021 - publications.aap.org
Incidence and Relapse of Idiopathic Nephrotic Syndrome: Meta-analysis | Pediatrics | American
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Molecular stratification of idiopathic nephrotic syndrome
MA Saleem - Nature Reviews Nephrology, 2019 - nature.com
Idiopathic nephrotic syndrome (INS) describes a group of pathologies of the renal
glomerulus that result in the classic triad of heavy proteinuria, oedema and …
glomerulus that result in the classic triad of heavy proteinuria, oedema and …
Evaluation of daily low-dose prednisolone during upper respiratory tract infection to prevent relapse in children with relapsing steroid-sensitive nephrotic syndrome …
Importance In children with corticosteroid-sensitive nephrotic syndrome, many relapses are
triggered by upper respiratory tract infections. Four small studies found that administration of …
triggered by upper respiratory tract infections. Four small studies found that administration of …
Transethnic, genome-wide analysis reveals immune-related risk alleles and phenotypic correlates in pediatric steroid-sensitive nephrotic syndrome
H Debiec, C Dossier, E Letouzé… - Journal of the …, 2018 - journals.lww.com
Background Steroid-sensitive nephrotic syndrome (SSNS) is a childhood disease with
unclear pathophysiology and genetic architecture. We investigated the genomic basis of …
unclear pathophysiology and genetic architecture. We investigated the genomic basis of …
[HTML][HTML] Prediction of short-and long-term outcomes in childhood nephrotic syndrome
SA Carter, S Mistry, J Fitzpatrick, T Banh… - Kidney international …, 2020 - Elsevier
Introduction It is unknown whether steroid sensitivity and other putative risk factors collected
at baseline can predict the disease course of idiopathic nephrotic syndrome in childhood …
at baseline can predict the disease course of idiopathic nephrotic syndrome in childhood …
Genetic identification of two novel loci associated with steroid-sensitive nephrotic syndrome
Background Steroid-sensitive nephrotic syndrome (SSNS), the most common form of
nephrotic syndrome in childhood, is considered an autoimmune disease with an established …
nephrotic syndrome in childhood, is considered an autoimmune disease with an established …