Idiopathic nephrotic syndrome in children

DG Noone, K Iijima, R Parekh - The Lancet, 2018 - thelancet.com
The incidence of idiopathic nephrotic syndrome (NS) is 1· 15–16· 9 per 100 000 children,
varying by ethnicity and region. The cause remains unknown but the pathogenesis of …

Nephrotic syndrome in infants and children: pathophysiology and management

ML Downie, C Gallibois, RS Parekh… - … and international child …, 2017 - Taylor & Francis
Nephrotic syndrome is defined by nephrotic-range proteinuria (≥ 40 mg/m2/hour or urine
protein/creatinine ratio≥ 200 mg/mL or 3+ protein on urine dipstick), hypoalbuminaemia (< …

Steroid sensitive nephrotic syndrome: revised guidelines

A Sinha, A Bagga, S Banerjee, K Mishra… - Asian Journal of …, 2021 - journals.lww.com
Objective: To frame revised guidelines on diagnosis, evaluation, management, and
supportive care of patients with the illness. Process: The guidelines combine evidence …

Efficacy of rituximab vs tacrolimus in pediatric corticosteroid-dependent nephrotic syndrome: a randomized clinical trial

B Basu, A Sander, B Roy, S Preussler, S Barua… - JAMA …, 2018 - jamanetwork.com
Importance Calcineurin inhibitors are an established first-line corticosteroid-sparing therapy
for patients with corticosteroid-dependent nephrotic syndrome (CDNS), whereas B …

Incidence and relapse of idiopathic nephrotic syndrome: meta-analysis

F Veltkamp, LR Rensma, AHM Bouts - Pediatrics, 2021 - publications.aap.org
Incidence and Relapse of Idiopathic Nephrotic Syndrome: Meta-analysis | Pediatrics | American
Academy of Pediatrics Skip to Main Content Disclaimer » Advertising AAP logo Search Close …

Molecular stratification of idiopathic nephrotic syndrome

MA Saleem - Nature Reviews Nephrology, 2019 - nature.com
Idiopathic nephrotic syndrome (INS) describes a group of pathologies of the renal
glomerulus that result in the classic triad of heavy proteinuria, oedema and …

Evaluation of daily low-dose prednisolone during upper respiratory tract infection to prevent relapse in children with relapsing steroid-sensitive nephrotic syndrome …

MT Christian, NJA Webb, S Mehta, RL Woolley… - JAMA …, 2022 - jamanetwork.com
Importance In children with corticosteroid-sensitive nephrotic syndrome, many relapses are
triggered by upper respiratory tract infections. Four small studies found that administration of …

Transethnic, genome-wide analysis reveals immune-related risk alleles and phenotypic correlates in pediatric steroid-sensitive nephrotic syndrome

H Debiec, C Dossier, E Letouzé… - Journal of the …, 2018 - journals.lww.com
Background Steroid-sensitive nephrotic syndrome (SSNS) is a childhood disease with
unclear pathophysiology and genetic architecture. We investigated the genomic basis of …

[HTML][HTML] Prediction of short-and long-term outcomes in childhood nephrotic syndrome

SA Carter, S Mistry, J Fitzpatrick, T Banh… - Kidney international …, 2020 - Elsevier
Introduction It is unknown whether steroid sensitivity and other putative risk factors collected
at baseline can predict the disease course of idiopathic nephrotic syndrome in childhood …

Genetic identification of two novel loci associated with steroid-sensitive nephrotic syndrome

S Dufek, C Cheshire, AP Levine… - Journal of the …, 2019 - journals.lww.com
Background Steroid-sensitive nephrotic syndrome (SSNS), the most common form of
nephrotic syndrome in childhood, is considered an autoimmune disease with an established …