The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

Ligand‐installed nanocarriers toward precision therapy

P Mi, H Cabral, K Kataoka - Advanced Materials, 2020 - Wiley Online Library
Abstract Development of drug‐delivery systems that selectively target neoplastic cells has
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …

Bio-inspired encapsulation and functionalization of iron oxide nanoparticles for biomedical applications

SO Aisida, PA Akpa, I Ahmad, T Zhao, M Maaza… - European polymer …, 2020 - Elsevier
Cancer cells are typified by proliferating mass of cells that grow faster than other smaller cell
tissues within the body. Efforts to combat this effect through chemotherapy, radiotherapy …

Peptide–nanoparticle conjugates: a next generation of diagnostic and therapeutic platforms?

W Jeong, J Bu, LJ Kubiatowicz, SS Chen, YS Kim… - Nano …, 2018 - Springer
Peptide–nanoparticle conjugates (PNCs) have recently emerged as a versatile tool for
biomedical applications. Synergism between the two promising classes of materials allows …

Nanonization strategies for poorly water-soluble drugs

H Chen, C Khemtong, X Yang, X Chang, J Gao - Drug discovery today, 2011 - Elsevier
Poor water solubility for many drugs and drug candidates remains a major obstacle to their
development and clinical application. Conventional formulations to improve solubility suffer …

Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases

ES Olson, T Jiang, TA Aguilera… - Proceedings of the …, 2010 - National Acad Sciences
High-resolution imaging of molecules intrinsically involved in malignancy and metastasis
would be of great value for clinical detection and staging of tumors. We now report in vivo …

[HTML][HTML] Superparamagnetic iron oxide nanoparticles: amplifying ROS stress to improve anticancer drug efficacy

G Huang, H Chen, Y Dong, X Luo, H Yu, Z Moore… - Theranostics, 2013 - ncbi.nlm.nih.gov
Superparamagnetic iron oxide nanoparticles (SPION) are an important and versatile nano-
platform with broad biological applications. Despite extensive studies, the biological and …

Nanomedicine in cancer therapy: innovative trends and prospects

E Blanco, A Hsiao, AP Mann, MG Landry… - Cancer …, 2011 - Wiley Online Library
Cancer is a leading cause of morbidity and mortality worldwide, with recent advancements
resulting in modest impacts on patient survival. Nanomedicine represents an innovative field …

[HTML][HTML] Improving the magnetic resonance imaging contrast and detection methods with engineered magnetic nanoparticles

J Huang, X Zhong, L Wang, L Yang, H Mao - Theranostics, 2012 - ncbi.nlm.nih.gov
Engineering and functionalizing magnetic nanoparticles have been an area of the extensive
research and development in the biomedical and nanomedicine fields. Because their …

Advancement in integrin facilitated drug delivery

D Arosio, C Casagrande - Advanced Drug Delivery Reviews, 2016 - Elsevier
The research of integrin-targeted anticancer agents has recorded important advancements
in ingenious design of delivery systems, based either on the prodrug approach, or on …