Incomplete response to Anti-VEGF therapy in neovascular AMD: Exploring disease mechanisms and therapeutic opportunities
PS Mettu, MJ Allingham, SW Cousins - Progress in retinal and eye …, 2021 - Elsevier
Intravitreal anti-vascular endothelial growth factor (VEGF) drugs have revolutionized the
treatment of neovascular age-related macular degeneration (NVAMD). However, many …
treatment of neovascular age-related macular degeneration (NVAMD). However, many …
Age‐related macular degeneration—emerging pathogenetic and therapeutic concepts
KM Gehrs, DH Anderson, LV Johnson… - Annals of …, 2006 - Taylor & Francis
Today, the average life expectancy in developed nations is over 80 years and climbing. And
yet, the quality of life during those additional years is often significantly diminished by the …
yet, the quality of life during those additional years is often significantly diminished by the …
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
GS Hageman, DH Anderson… - Proceedings of the …, 2005 - National Acad Sciences
Age-related macular degeneration (AMD) is the most frequent cause of irreversible
blindness in the elderly in developed countries. Our previous studies implicated activation of …
blindness in the elderly in developed countries. Our previous studies implicated activation of …
The role of inflammation in the pathogenesis of age-related macular degeneration
LA Donoso, D Kim, A Frost, A Callahan… - Survey of …, 2006 - Elsevier
Age-related macular degeneration (AMD), the leading cause of blindness in the elderly, is a
complex disease to study because of the potential role of demographic, environmental, and …
complex disease to study because of the potential role of demographic, environmental, and …
[HTML][HTML] Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration
E Kersten, CC Paun, RL Schellevis, CB Hoyng… - survey of …, 2018 - Elsevier
Biomarkers can help unravel mechanisms of disease and identify new targets for therapy.
They can also be useful in clinical practice for monitoring disease progression, evaluation of …
They can also be useful in clinical practice for monitoring disease progression, evaluation of …
The role of anti-inflammatory agents in age-related macular degeneration (AMD) treatment
Although age-related macular degeneration (AMD) is not a classic inflammatory disease like
uveitis, inflammation has been found to have an important role in disease pathogenesis and …
uveitis, inflammation has been found to have an important role in disease pathogenesis and …
Triple therapy for choroidal neovascularization due to age-related macular degeneration: verteporfin PDT, bevacizumab, and dexamethasone
AJ Augustin, S Puls, I Offermann - Retina, 2007 - journals.lww.com
Purpose: To evaluate the efficacy and safety of triple therapy with verteporfin photodynamic
therapy (PDT), dexamethasone, and bevacizumab in choroidal neovascularization (CNV) …
therapy (PDT), dexamethasone, and bevacizumab in choroidal neovascularization (CNV) …
Inflammation and age-related macular degeneration (AMD)
DG Telander - Seminars in ophthalmology, 2011 - Taylor & Francis
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly.
The cause of AMD is complex and many risk factors have been implicated including age …
The cause of AMD is complex and many risk factors have been implicated including age …
Autoimmunity in retinal degeneration: autoimmune retinopathy and age-related macular degeneration
K Morohoshi, AM Goodwin, M Ohbayashi… - Journal of autoimmunity, 2009 - Elsevier
Autoantibody production is associated with a variety of ocular disorders, including
autoimmune retinopathy (AIR) and age-related macular degeneration (AMD). A breakdown …
autoimmune retinopathy (AIR) and age-related macular degeneration (AMD). A breakdown …
Potential sources and roles of adaptive immunity in age‐related macular degeneration: shall we rename AMD into autoimmune macular disease?
S Camelo - Autoimmune diseases, 2014 - Wiley Online Library
Age‐related macular degeneration (AMD) is the leading cause of vision loss in the elderly
throughout the industrialized world. Its most prominent pathologic features are lesions …
throughout the industrialized world. Its most prominent pathologic features are lesions …