Ferroptosis is an iron-dependent cell death mechanism that may be important to prevent
tumor formation and useful as a target for new cancer therapies. Transcriptional networks …

We have found that the ketogenic (Keto) diet is able to, unexpectedly, promote the metastatic
potential of cancer cells in complementary mouse models. Notably, the Keto diet–induced …

Activating leucine-rich repeat kinase 2 (LRRK2) mutations cause Parkinson's and
phosphorylation of Rab10 by pathogenic LRRK2 blocks primary ciliogenesis in cultured …

Ferroptosis is a type of regulated cell death characterized by iron-dependent lipid
peroxidation. A model cell system is constructed to induce ferroptosis by re-expressing the …

BTB domain and CNC homolog 1 (BACH1) belongs to the family of basic leucine zipper
proteins and is expressed in most mammalian tissues. It can regulate its own expression …

BTB and CNC homology 1 (BACH1) represses the expression of genes involved in the
metabolism of iron, heme and reactive oxygen species. While BACH1 is rapidly degraded …

Epithelial–mesenchymal transition (EMT) is an important axis of phenotypic plasticity—a
hallmark of cancer metastasis. Raf kinase-B inhibitor protein (RKIP) and BTB and CNC …

Sickle cell disease (SCD) is an inherited hemoglobin disorder marked by red blood cell
sickling, resulting in severe anemia, painful episodes, extensive organ damage, and …

The protandric shrimp Hippolyte inermis is the only known marine invertebrate whose sex
determination is strongly influenced by the composition of its food. In H. inermis, a sex …

Abstract Changes in the absolute protein amounts of transcription factors are important for
regulating gene expression during cell differentiation and in responses to changes in the …