Accelerated MR spectroscopic imaging—a review of current and emerging techniques

W Bogner, R Otazo, A Henning - NMR in Biomedicine, 2021 - Wiley Online Library
Over more than 30 years in vivo MR spectroscopic imaging (MRSI) has undergone an
enormous evolution from theoretical concepts in the early 1980s to the robust imaging …

MRI with ultrahigh field strength and high-performance gradients: challenges and opportunities for clinical neuroimaging at 7 T and beyond

B Vachha, SY Huang - European Radiology Experimental, 2021 - Springer
Research in ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient
technology has provided enormous gains in sensitivity, resolution, and contrast for …

2-Hydroxyglutarate MR spectroscopy for prediction of isocitrate dehydrogenase mutant glioma: a systemic review and meta-analysis using individual patient data

CH Suh, HS Kim, SC Jung, CG Choi, SJ Kim - Neuro-oncology, 2018 - academic.oup.com
Background Noninvasive and accurate modality to predict isocitrate dehydrogenase (IDH)
mutant glioma may have great potential in routine clinical practice. We aimed to investigate …

Ultra-high-field MRI in the diagnosis and management of gliomas: a systematic review

A Shaffer, SS Kwok, A Naik, AT Anderson… - Frontiers in …, 2022 - frontiersin.org
Importance: Gliomas, tumors of the central nervous system, are classically diagnosed
through invasive surgical biopsy and subsequent histopathological study. Innovations in …

[HTML][HTML] Emerging methods and applications of ultra-high field MR spectroscopic imaging in the human brain

G Hangel, E Niess, P Lazen, P Bednarik, W Bogner… - Analytical …, 2022 - Elsevier
Abstract Magnetic Resonance Spectroscopic Imaging (MRSI) of the brain enables insights
into the metabolic changes and fluxes in diseases such as tumors, multiple sclerosis …

Meta-analysis and open-source database for in vivo brain Magnetic Resonance spectroscopy in health and disease

AT Gudmundson, A Koo, A Virovka, AL Amirault… - Analytical …, 2023 - Elsevier
Abstract Proton (1 H) Magnetic Resonance Spectroscopy (MRS) is a non-invasive tool
capable of quantifying brain metabolite concentrations in vivo. Prioritization of …

Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner

P Viswanath, M Radoul, JL Izquierdo-Garcia… - Cancer & …, 2018 - Springer
Background Magnetic resonance spectroscopy (MRS) studies have identified elevated
levels of the phospholipid precursor phosphocholine (PC) and phosphoethanolamine (PE) …

Application of 7T MRS to high-grade gliomas

L McCarthy, G Verma, G Hangel, A Neal… - American Journal of …, 2022 - ajnr.org
MRS, including single-voxel spectroscopy and MR spectroscopic imaging, captures
metabolites in high-grade gliomas. Emerging evidence indicates that 7T MRS may be more …

Inter‐subject stability and regional concentration estimates of 3D‐FID‐MRSI in the human brain at 7 T

G Hangel, B Spurny‐Dworak, P Lazen… - NMR in …, 2021 - Wiley Online Library
Purpose Recently, a 3D‐concentric ring trajectory (CRT)‐based free induction decay (FID)‐
MRSI sequence was introduced for fast high‐resolution metabolic imaging at 7 T. This …

Magnetic resonance spectroscopic assessment of isocitrate dehydrogenase status in gliomas: the new frontiers of spectrobiopsy in neurodiagnostics

A Di Ieva, JS Magnussen, J McIntosh, MJ Mulcahy… - World neurosurgery, 2020 - Elsevier
Background In the era of integrated genomic-histologic analysis of brain tumors, new
biomarkers have been introduced as diagnostic, prognostic, and therapeutic indicators. The …