[HTML][HTML] Biologics for tendon repair

D Docheva, SA Müller, M Majewski… - Advanced drug delivery …, 2015‏ - Elsevier
Tendon injuries are common and present a clinical challenge to orthopedic surgery mainly
because these injuries often respond poorly to treatment and require prolonged …

Tendon and ligament healing and current approaches to tendon and ligament regeneration

NL Leong, JL Kator, TL Clemens… - Journal of …, 2020‏ - Wiley Online Library
Ligament and tendon injuries are common problems in orthopedics. There is a need for
treatments that can expedite nonoperative healing or improve the efficacy of surgical repair …

Tendon tissue engineering: An overview of biologics to promote tendon healing and repair

V Citro, M Clerici, AR Boccaccini… - Journal of tissue …, 2023‏ - journals.sagepub.com
Tendons are dense connective tissues with a hierarchical polarized structure that respond to
and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion …

Therapeutic use of mesenchymal stromal cells: the need for inclusive characterization guidelines to accommodate all tissue sources and species

A Wright, ML Arthaud-Day, ML Weiss - Frontiers in cell and …, 2021‏ - frontiersin.org
Following their discovery over 50 years ago, mesenchymal stromal cells (MSCs) have
become one of the most studied cellular therapeutic products by both academia and industry …

Biologic augmentation of rotator cuff repair with mesenchymal stem cells during arthroscopy improves healing and prevents further tears: a case-controlled study

P Hernigou, CH Flouzat Lachaniette, J Delambre… - International …, 2014‏ - Springer
Purpose The purpose of this study was to evaluate the efficiency of biologic augmentation of
rotator cuff repair with iliac crest bone marrow-derived mesenchymal stem cells (MSCs). The …

Decellularized tissue and cell-derived extracellular matrices as scaffolds for orthopaedic tissue engineering

CW Cheng, LD Solorio, E Alsberg - Biotechnology advances, 2014‏ - Elsevier
The reconstruction of musculoskeletal defects is a constant challenge for orthopaedic
surgeons. Musculoskeletal injuries such as fractures, chondral lesions, infections and tumor …

Mammalian MSC from selected species: Features and applications

C Uder, S Brückner, S Winkler… - Cytometry Part …, 2018‏ - Wiley Online Library
Mesenchymal stromal/stem cells (MSC) are promising candidates for cellular therapy of
different diseases in humans and in animals. Following the guidelines of the International …

High cholesterol induces apoptosis and autophagy through the ROS-activated AKT/FOXO1 pathway in tendon-derived stem cells

K Li, Y Deng, G Deng, P Chen, Y Wang, H Wu… - Stem cell research & …, 2020‏ - Springer
Background Hypercholesterolemia increases the risk of tendon pain and tendon rupture.
Tendon-derived stem cells (TDSCs) play a vital role in the development of tendinopathy. Our …

Tendon biomechanics and mechanobiology—a minireview of basic concepts and recent advancements

JHC Wang, Q Guo, B Li - Journal of hand therapy, 2012‏ - Elsevier
Due to their unique hierarchical structure and composition, tendons possess characteristic
biomechanical properties, including high mechanical strength and viscoelasticity, which …

[HTML][HTML] Mesenchymal stem cells empowering tendon regenerative therapies

R Costa-Almeida, I Calejo, ME Gomes - International journal of molecular …, 2019‏ - mdpi.com
Tendon tissues have limited healing capacity. The incidence of tendon injuries and the
unsatisfactory functional outcomes of tendon repair are driving the search for alternative …