[HTML][HTML] Sample preparation strategies for mass spectrometry analysis in human exposome research: current status and future perspectives

Y Gu, JT Peach, B Warth - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The exposome is the measure of total environmental exposures and has a significant impact
on human health outcomes. Exposomics research typically examines complex biological …

Exposure to novel brominated flame retardants and organophosphate esters and associations with thyroid cancer risk: A case–control study in eastern China

M Liu, A Li, L Meng, G Zhang, X Guan… - Environmental …, 2022 - ACS Publications
Novel brominated flame retardant (NBFR) and organophosphate ester (OPE) exposure may
engender adverse effects on human health. However, present epidemiological information …

Phospholipid removal for enhanced chemical exposomics in human plasma

K Sdougkou, H **e, S Papazian… - Environmental …, 2023 - ACS Publications
The challenge of chemical exposomics in human plasma is the 1000-fold concentration gap
between endogenous substances and environmental pollutants. Phospholipids are the …

Addressing exposome: an innovative approach to environmental determinants in pediatric respiratory health

G Ferrante, S Fasola, G Cilluffo, G Piacentini… - Frontiers in Public …, 2022 - frontiersin.org
Developmental age is particularly vulnerable to impacts of environmental exposures. Until
recent years, the field of environment and child health has predominantly relied on the study …

Simultaneous effervescence-assisted microextraction and magnetic adsorbent generation for rapid and cost-effective organochlorine pesticides analysis

W Li, Q Zhang, Y Liu, B Deng, Y Zheng, J Li, D Chen - Food Chemistry, 2024 - Elsevier
This study introduced an innovative magnetic effervescence-assisted microextraction
method, streamlining the preparation of effervescent tablets through a one-pot method that …

An Enhanced Protocol to Expand Human Exposome and Machine Learning-Based Prediction for Methodology Application

A He, Y Yao, S Chen, Y Li, N **ao, H Chen… - Environmental …, 2025 - ACS Publications
The human exposome remains limited due to the challenging analytical strategies used to
reveal low-level endocrine-disrupting chemicals (EDCs) and their metabolites in serum and …

Novel biomonitoring method for determining five classes of legacy and alternative flame retardants in human serum samples

X Guan, G Zhang, L Meng, M Liu, L Zhang… - Journal of …, 2023 - Elsevier
Flame retardants (FRs) are ubiquitous in environment and biota and may pose harm to
human health. In recent years, concern regarding legacy and alternative FRs has been …

Chemical Exposomics in Human Plasma by Lipid Removal and Large-Volume Injection Gas Chromatography–High-Resolution Mass Spectrometry

H **e, K Sdougkou, B Bonnefille… - Environmental …, 2024 - ACS Publications
For comprehensive chemical exposomics in blood, analytical workflows are evolving
through advances in sample preparation and instrumental methods. We hypothesized that …

Micro-solid phase extraction with in-lab-packed columns for cost-efficient drug extraction from urine samples

A Chromiec, R Wietecha-Posłuszny - Monatshefte für Chemie-Chemical …, 2024 - Springer
This study introduces a miniaturised solid-phase extraction (µ-SPE) method coupled with
ultra-high performance liquid chromatography and tandem mass spectrometry (UHPLC …

[HTML][HTML] Exposure to flame retardants in European children—Results from the HBM4EU aligned studies

V van Der Schyff, J Kalina, E Govarts, L Gilles… - International journal of …, 2023 - Elsevier
Many legacy and emerging flame retardants (FRs) have adverse human and environmental
health effects. This study reports legacy and emerging FRs in children from nine European …