[HTML][HTML] Cell sources for cultivated meat: applications and considerations throughout the production workflow

J Reiss, S Robertson, M Suzuki - International Journal of Molecular …, 2021 - mdpi.com
Cellular agriculture is an emerging scientific discipline that leverages the existing principles
behind stem cell biology, tissue engineering, and animal sciences to create agricultural …

[HTML][HTML] Advances and challenges in stem cell culture

C McKee, GR Chaudhry - Colloids and surfaces B: Biointerfaces, 2017 - Elsevier
Stem cells (SCs) hold great promise for cell therapy, tissue engineering, and regenerative
medicine as well as pharmaceutical and biotechnological applications. They have the …

Clinical-grade stem cell–derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs

R Sharma, V Khristov, A Rising, BS Jha… - Science translational …, 2019 - science.org
Considerable progress has been made in testing stem cell–derived retinal pigment
epithelium (RPE) as a potential therapy for age-related macular degeneration (AMD) …

[HTML][HTML] Progress and challenges in large-scale expansion of human pluripotent stem cells

C Kropp, D Massai, R Zweigerdt - Process Biochemistry, 2017 - Elsevier
The constant supply of high cell numbers generated by defined, robust, and economically
viable culture processes is indispensable for the envisioned application of human …

Influence of microenvironment on mesenchymal stem cell therapeutic potency: from planar culture to microcarriers

AC Tsai, R Jeske, X Chen, X Yuan, Y Li - Frontiers in Bioengineering …, 2020 - frontiersin.org
Human mesenchymal stem cells (hMSCs) are a promising candidate in cell therapy as they
exhibit multilineage differentiation, homing to the site of injury, and secretion of trophic …

Attachment and detachment strategies in microcarrier-based cell culture technology: A comprehensive review

S Derakhti, SH Safiabadi-Tali, G Amoabediny… - Materials Science and …, 2019 - Elsevier
Achieving a high cell density of animal cells is a prerequisite for different medical
applications such as cell therapy, tissue engineering, and vaccine production. Microcarrier …

Efficient large-scale 2D culture system for human induced pluripotent stem cells and differentiated cardiomyocytes

S Tohyama, J Fujita, C Fujita, M Yamaguchi… - Stem cell reports, 2017 - cell.com
Cardiac regenerative therapies utilizing human induced pluripotent stem cells (hiPSCs) are
hampered by ineffective large-scale culture. hiPSCs were cultured in multilayer culture …

[HTML][HTML] Modeling cardiac disease mechanisms using induced pluripotent stem cell-derived cardiomyocytes: progress, promises and challenges

EI Parrotta, V Lucchino, L Scaramuzzino… - International Journal of …, 2020 - mdpi.com
Cardiovascular diseases (CVDs) are a class of disorders affecting the heart or blood
vessels. Despite progress in clinical research and therapy, CVDs still represent the leading …

Suspension culture improves iPSC expansion and pluripotency phenotype

N Cuesta-Gomez, K Verhoeff, N Dadheech… - Stem Cell Research & …, 2023 - Springer
Background Induced pluripotent stem cells (iPSCs) offer potential to revolutionize
regenerative medicine as a renewable source for islets, dopaminergic neurons, retinal cells …

Human-induced pluripotent stem cells in cardiovascular research: current approaches in cardiac differentiation, maturation strategies, and scalable production

D Thomas, NJ Cunningham, S Shenoy… - Cardiovascular …, 2022 - academic.oup.com
Manifestations of cardiovascular diseases (CVDs) in a patient or a population differ based
on inherent biological makeup, lifestyle, and exposure to environmental risk factors. These …