Tumor biomarkers, the substances which are produced by tumors or the body's responses to
tumors during tumorigenesis and progression, have been demonstrated to possess critical …

Simple Summary CA125 has been the most promising biomarker for screening ovarian
cancer; however, it still does not have an acceptable accuracy in population-based …

Ovarian cancer is the 5th leading cause of death for women with cancer worldwide. In more
than 70% of cases, it is only diagnosed at an advanced stage. Our study aims to give an …

Glycosylation is a well-regulated cell and microenvironment specific post-translational
modification. Several glycosyltransferases and glycosidases orchestrate the addition of …

After it was discovered approximately 40 years ago, carbohydrate antigen 125 (CA125)
became the most widely used and concerning biomarker in ovarian cancer screening …

PURPOSE Single-agent PD-1 blockade exhibits limited efficacy in epithelial ovarian cancer
(EOC). We evaluated ipilimumab plus nivolumab compared with nivolumab alone in women …

Ovarian cancer (OC) is the most lethal gynaecologic malignancy, attributed to its insidious
growth, non-specific symptoms and late presentation. Unfortunately, current screening …

The ability to identify ovarian cancer (OC) at its earliest stages remains a challenge. The
patients present an advanced stage at diagnosis. This heterogeneous disease has …

Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

Interest in precision diagnostics has been fuelled by the concept that early detection of
cancer would benefit patients; that is, if detected early, more tumours should be resectable …