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Toxicity testing in the 21st century: progress in the past decade and future perspectives
D Krewski, ME Andersen, MG Tyshenko… - Archives of …, 2020 - Springer
Advances in the biological sciences have led to an ongoing paradigm shift in toxicity testing
based on expanded application of high-throughput in vitro screening and in silico methods …
based on expanded application of high-throughput in vitro screening and in silico methods …
Integrating tools for non-targeted analysis research and chemical safety evaluations at the US EPA
Tens-of-thousands of chemicals are registered in the US for use in countless processes and
products. Recent evidence suggests that many of these chemicals are measureable in …
products. Recent evidence suggests that many of these chemicals are measureable in …
The CompTox Chemistry Dashboard: a community data resource for environmental chemistry
AJ Williams, CM Grulke, J Edwards… - Journal of …, 2017 - Springer
Despite an abundance of online databases providing access to chemical data, there is
increasing demand for high-quality, structure-curated, open data to meet the various needs …
increasing demand for high-quality, structure-curated, open data to meet the various needs …
The next generation blueprint of computational toxicology at the US Environmental Protection Agency
RS Thomas, T Bahadori, TJ Buckley… - Toxicological …, 2019 - academic.oup.com
Abstract The US Environmental Protection Agency (EPA) is faced with the challenge of
efficiently and credibly evaluating chemical safety often with limited or no available toxicity …
efficiently and credibly evaluating chemical safety often with limited or no available toxicity …
The Chemical and Products Database, a resource for exposure-relevant data on chemicals in consumer products
Quantitative data on product chemical composition is a necessary parameter for
characterizing near-field exposure. This data set comprises reported and predicted …
characterizing near-field exposure. This data set comprises reported and predicted …
[HTML][HTML] Chemicals of concern in plastic toys
We present a list of Chemicals of Concern (CoCs) in plastic toys. We started from available
studies reporting chemical composition of toys to group plastic materials, as well as to gather …
studies reporting chemical composition of toys to group plastic materials, as well as to gather …
Allergic diseases: a comprehensive review on risk factors, immunological mechanisms, link with COVID-19, potential treatments, and role of allergen bioinformatics
FM Aldakheel - International journal of environmental research and …, 2021 - mdpi.com
The prevalence of allergic diseases is regarded as one of the key challenges in health
worldwide. Although the precise mechanisms underlying this rapid increase in prevalence …
worldwide. Although the precise mechanisms underlying this rapid increase in prevalence …
Suspect screening analysis of chemicals in consumer products
KA Phillips, A Yau, KA Favela, KK Isaacs… - … science & technology, 2018 - ACS Publications
A two-dimensional gas chromatography-time-of-flight/mass spectrometry (GC× GC-TOF/MS)
suspect screening analysis method was used to rapidly characterize chemicals in 100 …
suspect screening analysis method was used to rapidly characterize chemicals in 100 …
[HTML][HTML] Health risks of chemicals in consumer products: A review
Increasingly diverse chemicals are used in consumer products, while our understanding of
their exposure pathways and associated human health risks still lags behind. This paper …
their exposure pathways and associated human health risks still lags behind. This paper …
[HTML][HTML] Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes
E Fritsche, P Grandjean, KM Crofton, M Aschner… - Toxicology and applied …, 2018 - Elsevier
This consensus statement voices the agreement of scientific stakeholders from regulatory
agencies, academia and industry that a new framework needs adopting for assessment of …
agencies, academia and industry that a new framework needs adopting for assessment of …