Cisplatin-Induced Kidney Toxicity: Potential Roles of Major NAD+-Dependent Enzymes and Plant-Derived Natural Products
A Iskander, LJ Yan - Biomolecules, 2022 - mdpi.com
Cisplatin is an FDA approved anti-cancer drug that is widely used for the treatment of a
variety of solid tumors. However, the severe adverse effects of cisplatin, particularly kidney …
variety of solid tumors. However, the severe adverse effects of cisplatin, particularly kidney …
Virucidal Activity of Essential Oils From Citrus x aurantium L. Against Influenza A Virus H1N1:Limonene as a Potential Household Disinfectant Against Virus
NQ Fadilah, A Jittmittraphap… - Natural Product …, 2022 - journals.sagepub.com
This work explored the compositions of a crude extract of peels of Citrus x aurantium using a
gas chromatography-mass spectrometry (GC-MS) technique. The crude extract of peels of …
gas chromatography-mass spectrometry (GC-MS) technique. The crude extract of peels of …
The preventative effect of Baihe Gu** Pill on cisplatin-induced acute kidney injury by activating the PI3K/AKT and suppressing the NF-κB/MAPK pathways
X Li, J Shi, Y Teng, Z Liu - Journal of Ethnopharmacology, 2024 - Elsevier
Abstract Ethnopharmacological relevance Baihe Gu** Pill (BHGJP) is a traditional Chinese
medicine (TCM) derived from the “Collection of Medical Formulas”. BHGJP is applied to treat …
medicine (TCM) derived from the “Collection of Medical Formulas”. BHGJP is applied to treat …
p-Synephrine ameliorates alloxan-induced diabetes mellitus through inhibiting oxidative stress and inflammation via suppressing the NF-kappa B and MAPK …
YL Wang, SX Lin, Y Wang, T Liang, T Jiang, P Liu… - Food & Function, 2023 - pubs.rsc.org
Oxidative stress and inflammation play important roles in the development of diabetes
mellitus. p-Synephrine, the primary pharmacologically active protoalkaloid in Citrus species …
mellitus. p-Synephrine, the primary pharmacologically active protoalkaloid in Citrus species …
Phenolics in Citrus aurantium fruit identified by UHPLC-MS/MS and their bioactivities
L Wen, M He, C Yin, Y Jiang, D Luo, B Yang - LWT, 2021 - Elsevier
Sour orange (Citrus aurantium) is a popular fruit with health benefits. Phenolics are the
dominant bioactive compounds in this fruit. However, the full phenolics composition remains …
dominant bioactive compounds in this fruit. However, the full phenolics composition remains …
[HTML][HTML] Evaluation of the hepatoprotective activity of hydroalcoholic extract of Alhagi camelorum against valproic acid-induced hepatotoxicity in rats
MO Iqbal, M Manzoor, A Mumtaz, R Riaz… - Biomedicine & …, 2022 - Elsevier
Background and purpose Despite many liver disorders, clinically useful drugs are scarce.
Moreover, the available therapies are facing the challenges of efficacy and safety. Alhagi …
Moreover, the available therapies are facing the challenges of efficacy and safety. Alhagi …
Nephroprotective Effects of Alhagi camelorum against Cisplatin-Induced Nephrotoxicity in Albino Wistar Rats
Alhagi camelorum (AC) is an old plant with a significant therapeutic value throughout Africa,
Asia, and Latin America. The overuse of cisplatin (Cis> 50 mg/m2) is associated with …
Asia, and Latin America. The overuse of cisplatin (Cis> 50 mg/m2) is associated with …
The nephroprotective effects of Daucus carota and Eclipta prostrata against cisplatin-induced nephrotoxicity in rats
MO Iqbal, AS Sial, I Akhtar, M Naeem, A Hazafa… - …, 2021 - Taylor & Francis
The overuse of cisplatin (> 50 mg/m2) is limited to nephrotoxicity, ototoxicity, gastrotoxicity,
myelosuppression, and allergic reactions. The objective of this study was to investigate the …
myelosuppression, and allergic reactions. The objective of this study was to investigate the …
Multi-mechanistic and therapeutic exploration of nephroprotective effect of traditional ayurvedic polyherbal formulation using in silico, in vitro and in vivo approaches
Based on traditional therapeutic claims, NEERI KFT (a traditional Ayurvedic polyherbal
preparation) has been innovatively developed in recent time on the decades of experience …
preparation) has been innovatively developed in recent time on the decades of experience …
[HTML][HTML] Biochemical evaluation and medicinal ability of Jatropha mollissima in hepatic disorders
MO Iqbal, M Naeem, A Mumtaz… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Objective: Jatropha mollissima is one of the most valuable medicinal plants used for the
treatment of hepatic disorders. It is evident that 500 mg/kg of sodium valproate causes the …
treatment of hepatic disorders. It is evident that 500 mg/kg of sodium valproate causes the …