The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an
evolutionary or rather a revolutionary conceptualization of the immune changes in response …

Adipose tissue derived stem cells (ADSCs) are mesenchymal stem cells identified within
subcutaneous tissue at the base of the hair follicle (dermal papilla cells), in the dermal …

INTRODUCTION All body cells rely on blood vessels (BVs) for the provision of oxygen and
other blood-borne substances and, in certain settings, also for the provision of endothelial …

We pursued a study of immune responses in coronavirus disease 2019 (COVID-19) and
influenza patients. Compared to patients with influenza, patients with COVID-19 exhibited …

Aging is associated with an increased risk of cardiovascular disease and death. Here we
show that oral supplementation of the natural polyamine spermidine extends the lifespan of …

Risk for or established malnutrition is frequent in older adults, accompanied by functional
limitations, increased morbidity and mortality. Protein-energy malnutrition is often observed …

Inflammatory reactions could be both beneficial and detrimental to the brain, depending on
strengths of their activation in various stages of neurodegeneration. Mild activation of …

Inflammation is a cellular response to factors that challenge the homeostasis of cells and
tissues. Cell-associated and soluble pattern-recognition receptors, eg Toll-like receptors …

Inflamm‐aging is a challenging and promising new branch of aging‐related research fields
that includes areas such as immunosenescence. Increasing evidence indicates that inflamm …

In order to better understand the pathogenesis of Parkinson's Disease (PD) it is important to
consider possible contributory factors inherent to the aging process, as age-related changes …