As part of a program to assess the adverse biological effects expected from astronauts'
exposure to space radiation, numerous different biological effects relating to astronauts' …

During space travel astronauts are exposed to a variety of radiations, including galactic
cosmic rays composed of high-energy protons and high-energy charged (HZE) nuclei, and …

Ionizing radiation-induced oxidative stress is attributed to generation of reactive oxygen
species (ROS) due to radiolysis of water molecules and is short lived. Persistent oxidative …

Proliferative gastrointestinal (GI) tissue is radiation-sensitive, and heavy-ion space radiation
with its high-linear energy transfer (high-LET) and higher damaging potential than low-LET γ …

Medical responders to radiological and nuclear disasters currently lack sufficient high-
throughput and minimally invasive biodosimetry tools to assess exposure and injury in the …

Despite recent epidemiological evidences linking radiation exposure and a number of
human ailments including cancer, mechanistic understanding of how radiation inflicts long …

Astronauts on multi-year interplanetary missions will be exposed to a low, chronic dose of
high-energy, high-charge particles. Studies in rodents show acute, nonfractionated …

Risk of colorectal cancer (CRC) after exposure to low linear energy transfer (low-LET)
radiation such as γ-ray is highlighted by the studies in atom bomb survivors. On the contrary …

Tissue consequences of radiation exposure are dependent on radiation quality and high
linear energy transfer (high-LET) radiation, such as heavy ions in space is known to deposit …

Purpose There are uncertainties associated with the prediction of colorectal cancer (CRC)
risk from highly energetic heavy ion (HZE) radiation. We undertook a comprehensive …