Bladder cancer is a heterogeneous malignancy and is responsible for approximately 3.2%
of new diagnoses of cancer per year (Sung et al., 2021). Fibroblast Growth Factor Receptors …

Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR)
signaling has crucial roles in a multitude of processes during embryonic development and …

Receptor tyrosine kinases (RTKs) are transmembrane cell-surface proteins that act as signal
transducers. They regulate essential cellular processes like proliferation, apoptosis …

In the past two decades, several molecular targeted inhibitors have been developed and
evaluated clinically to improve the survival of patients with cancer. Molecular targeted …

The sites of targeted therapy are limited and need to be expanded. The FGF‐FGFR
signalling plays pivotal roles in the oncogenic process, and FGF/FGFR inhibitors are a …

(1) Background: The oncology field has drastically changed with the advent of precision
medicine, led by the discovery of druggable genes or immune targets assessed through next …

FGFR signaling is deregulated in many human cancers, and FGFR is considered a valid
target in FGFR-deregulated tumors. Here, we examine the preclinical profile of futibatinib …

Human malignancies are often the result of overexpressed and constitutively active receptor
and non-receptor tyrosine kinases, which ultimately lead to the mediation of key tumor …

This review article proposes a comprehensive report of the design strategies engaged in the
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …

The FGFR signaling pathway is integral to cellular activities, including proliferation,
differentiation, and survival. Dysregulation of this pathway is implicated in numerous human …