Polyphenols: Immunonutrients tip** the balance of immunometabolism in chronic diseases

C Ferreira, P Vieira, H Sá, J Malva… - Frontiers in …, 2024 - frontiersin.org
Mounting evidence progressively appreciates the vital interplay between immunity and
metabolism in a wide array of immunometabolic chronic disorders, both autoimmune and …

Filling the gaps on stroke research: Focus on inflammation and immunity

D Levard, I Buendia, A Lanquetin, M Glavan… - Brain, Behavior, and …, 2021 - Elsevier
For the last two decades, researchers have placed hopes in a new era in which a
combination of reperfusion and neuroprotection would revolutionize the treatment of stroke …

YTHDC1 mitigates ischemic stroke by promoting Akt phosphorylation through destabilizing PTEN mRNA

Z Zhang, Q Wang, X Zhao, L Shao, G Liu, X Zheng… - Cell death & …, 2020 - nature.com
Abstract YTH Domain Containing 1 (YTHDC1) is one of the m6A readers that is essential for
oocyte development and tumor progression. The role of YTHDC1 in neuronal survival and …

Neutrophil–lymphocyte ratio in acute ischemic stroke: Immunopathology, management, and prognosis

D Sharma, KJ Spring… - Acta Neurologica …, 2021 - Wiley Online Library
There is an ongoing need for accurate prognostic biomarkers in the milieu of acute ischemic
stroke (AIS) receiving reperfusion therapy. Neutrophil–lymphocyte ratio (NLR) has been …

Native and bioengineered exosomes for ischemic stroke therapy

H Khan, JJ Pan, Y Li, Z Zhang, GY Yang - Frontiers in Cell and …, 2021 - frontiersin.org
Exosomes are natural cells-derived vesicles, which are at the forefront toward clinical
success for various diseases, including cerebral ischemia. Exosomes mediate cell-to-cell …

Cerebral edema after ischemic stroke: Pathophysiology and underlying mechanisms

Y Gu, C Zhou, Z Piao, H Yuan, H Jiang, H Wei… - Frontiers in …, 2022 - frontiersin.org
Ischemic stroke is associated with increasing morbidity and has become the main cause of
death and disability worldwide. Cerebral edema is a serious complication arising from …

Volumetric distribution of perivascular space in relation to mild cognitive impairment

F Sepehrband, G Barisano, N Sheikh-Bahaei… - Neurobiology of …, 2021 - Elsevier
Vascular contributions to early cognitive decline are increasingly recognized, prompting
further investigation into the nature of related changes in perivascular spaces (PVS). Using …

Traditional Chinese medicine use in the pathophysiological processes of intracerebral hemorrhage and comparison with conventional therapy

T Duan, L Li, Y Yu, T Li, R Han, X Sun, Y Cui… - Pharmacological …, 2022 - Elsevier
Intracerebral hemorrhage (ICH) refers to hemorrhage caused by non-traumatic vascular
rupture in the brain parenchyma, which is characterized by acute onset, severe illness, and …

Systemic immune-inflammation index predicts 3-month functional outcome in acute ischemic stroke patients treated with intravenous thrombolysis

Y Weng, T Zeng, H Huang, J Ren, J Wang… - … Interventions in Aging, 2021 - Taylor & Francis
Background and Purpose Systemic immune-inflammation index (SII), a novel inflammation
index derived from counts of circulating platelets, neutrophils and lymphocytes, has been …

[HTML][HTML] Molecular mechanisms of neuroimmune crosstalk in the pathogenesis of stroke

YH Choi, C Laaker, M Hsu, P Cismaru… - International Journal of …, 2021 - mdpi.com
Stroke disrupts the homeostatic balance within the brain and is associated with a significant
accumulation of necrotic cellular debris, fluid, and peripheral immune cells in the central …