Research priorities for the primordial prevention of acute rheumatic fever and rheumatic heart disease by modifying the social determinants of health

MG Baker, MY Masterson, M Shung-King, A Beaton… - BMJ global …, 2023 - gh.bmj.com
The social determinants of health (SDH), such as access to income, education, housing and
healthcare, strongly shape the occurrence of acute rheumatic fever (ARF) and rheumatic …

The rise and fall of acute rheumatic fever and rheumatic heart disease: a mini review

Y Liang, D Yu, Q Lu, Y Zheng, Y Yang - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Introduction The incidences of acute rheumatic fever (ARF) and rheumatic heart disease
(RHD), which were leading causes of death in children in the 1920s, have decreased …

Risk factors for acute rheumatic fever: a case-control study

MG Baker, J Gurney, NJ Moreland… - The Lancet Regional …, 2022 - thelancet.com
Background Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) remain an
inequitable cause of avoidable suffering and early death in many countries, including …

A worldwide population of Streptococcus pyogenes strains circulating among school-aged children in Auckland, New Zealand: a genomic epidemiology analysis

JA Lacey, J Bennett, TB James, BS Hines… - The Lancet Regional …, 2024 - thelancet.com
Background Acute rheumatic fever (ARF) is a serious post-infectious sequala of Group A
Streptococcus (GAS, Streptococcus pyogenes). In New Zealand (NZ) ARF is a major cause …

Prevalence, antibiotic susceptibility profile and associated factors of group A Streptococcal pharyngitis among pediatric patients with acute pharyngitis in Gondar …

M Tadesse, Y Hailu, S Biset, G Ferede… - Infection and Drug …, 2023 - Taylor & Francis
Background Streptococcus pyogenes (S. pyogenes) or group A streptococcus is a common
cause of bacterial pharyngitis in children. Since it is difficult to distinguish between viral and …

Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infections

J Osowicki, HR Frost, KI Azzopardi… - Nature …, 2024 - nature.com
Abstract Knowledge gaps regarding human immunity to Streptococcus pyogenes have
impeded vaccine development. To address these gaps and evaluate vaccine candidates …

Cytokine imbalance in acute rheumatic fever and rheumatic heart disease: Mechanisms and therapeutic implications

FM Middleton, R McGregor, RH Webb, NJ Wilson… - Autoimmunity …, 2022 - Elsevier
Abstract Acute Rheumatic Fever (ARF) and Rheumatic Heart Disease (RHD) are
autoimmune sequelae of Group A Streptococcus infection with significant global disease …

He Kāinga Oranga: reflections on 25 years of measuring the improved health, wellbeing and sustainability of healthier housing

P Howden-Chapman, J Crane, M Keall… - Journal of the Royal …, 2024 - Taylor & Francis
This paper reflects on the influences and outcomes of He Kāinga Oranga/Housing and
Health Research Programme over 25 years, and their impact on housing and health policy …

Systematic review of household transmission of Strep A: a potential site for prevention that has eluded attention

SL Enkel, S Barnes, J Daw, E Pearson… - The Journal of …, 2024 - academic.oup.com
Abstract Background Although Streptococcus pyogenes (Strep A) is the sixth-most common
infectious disease globally, its transmission within the household remains an understudied …

[HTML][HTML] Development and characterization of a hemolysis inhibition assay to determine functionality of anti-Streptolysin O antibodies in human sera

M Carducci, A Whitcombe, L Rovetini, L Massai… - Journal of …, 2024 - Elsevier
The high burden of disease and the long-lasting sequelae following Streptococcus
pyogenes (Strep A) infections make the development of an effective vaccine a global health …