Background Overviews of systematic reviews are a relatively new approach to synthesising
evidence, and research methods and associated guidance are develo**. Within this paper …

Background Overviews of reviews (overviews) compile information from multiple systematic
reviews (SRs) to provide a single synthesis of relevant evidence for decision-making. It is …

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Background Studies in adults and adolescents have demonstrated that tiotropium is
efficacious as an add-on therapy to inhaled corticosteroids (ICSs) with or without other …

Background Asthma patients who continue to experience symptoms despite taking regular
inhaled corticosteroids (ICS) represent a management challenge. Long‐acting beta2 …

Background Bronchiectasis is a chronic respiratory disease characterised by abnormal
dilatation of the bronchi, and presents typically with a chronic productive cough (or chronic …

Background Long‐acting beta 2‐agonists (LABA) in combination with inhaled
corticosteroids (ICS) are increasingly prescribed for children with asthma. Objectives To …

Background Asthma is a common respiratory disease among both adults and children and
short acting inhaled beta‐2 agonists are used widely for'reliever'bronchodilator therapy …

Objective To systematically review the literature and determine frequencies of adverse drug
events (ADE) associated with pediatric asthma medications. Methods Following PRISMA …

Abstract Background and Objective As systematic reviews may run out of date, it might be
necessary to update them. Out-of-date reviews may jeopardize the comparability when used …