Simple Summary Glioblastoma multiforme (GBM) is one of the most aggressive
malignancies, accounting for 14.5% of all central nervous system tumors and 48.6% of …

• Early symptoms of brain tumours in adults are non-specific, and patients may present
multiple times to primary care services before they are referred for investigation. Look for …

The protective blood–brain barrier has a major role in ensuring normal brain function by
severely limiting and tightly controlling the ingress of substances into the brain from the …

Therapeutic checkpoint antibodies blocking programmed death receptor 1/programmed
death ligand 1 (PD-L1) signaling have radically improved clinical outcomes in cancer …

Animals constantly receive various sensory stimuli, such as odours, sounds, light and touch,
from the surrounding environment. These sensory inputs are essential for animals to search …

Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …

Gliomas are the most common primary intracranial tumor, representing 81% of malignant
brain tumors. Although relatively rare, they cause significant mortality and morbidity …

We have extended our understanding of the molecular biology that underlies adult
glioblastoma over many years. By contrast, high-grade gliomas in children and adolescents …

Glioblastomas,(grade 4 astrocytomas), are aggressive primary brain tumors characterized
by histopathological heterogeneity. High-resolution sequencing technologies have shown …

Background Differentiation between glioblastoma and brain metastasis is highly important
due to differing medical treatment strategies. While MRI is the modality of choice for the …