Microsecond and nanosecond electric pulses in cancer treatments
M Breton, LM Mir - Bioelectromagnetics, 2012 - Wiley Online Library
New local treatments based on electromagnetic fields have been developed as non‐
surgical and minimally invasive treatments of tumors. In particular, short electric pulses can …
surgical and minimally invasive treatments of tumors. In particular, short electric pulses can …
[HTML][HTML] A molecular insight into the electro-transfer of small molecules through electropores driven by electric fields
The transport of chemical compounds across the plasma membrane into the cell is relevant
for several biological and medical applications. One of the most efficient techniques to …
for several biological and medical applications. One of the most efficient techniques to …
Molecular dynamics simulations of lipid membrane electroporation
The permeability of cell membranes can be transiently increased following the application of
external electric fields. Theoretical approaches such as molecular modeling provide a …
external electric fields. Theoretical approaches such as molecular modeling provide a …
High-frequency submicrosecond electroporator
In this work, we present a novel electroporator which is capable of generating single and
bursts of high power (3 kV, 60 A) square wave pulses of variable duration (100 ns to 1 ms) …
bursts of high power (3 kV, 60 A) square wave pulses of variable duration (100 ns to 1 ms) …
Activation of intracellular phosphoinositide signaling after a single 600 nanosecond electric pulse
Exposure to nanosecond pulsed electrical fields (nsPEFs) results in a myriad of observable
effects in mammalian cells. While these effects are often attributed to the direct …
effects in mammalian cells. While these effects are often attributed to the direct …
Effects of time delay between unipolar pulses in high frequency nano-electrochemotherapy
Objective: this work focuses on bleomycin electrochemotherapy using new modality of high
repetition frequency unipolar nanosecond pulses. Methods: As a tumor model, Lewis lung …
repetition frequency unipolar nanosecond pulses. Methods: As a tumor model, Lewis lung …
Concepts and capabilities of in-house built nanosecond pulsed electric field (nsPEF) generators for electroporation: State of art
P Butkus, A Murauskas, S Tolvaišienė, V Novickij - Applied Sciences, 2020 - mdpi.com
Electroporation is a pulsed electric field triggered phenomenon of cell permeabilization,
which is extensively used in biomedical and biotechnological context. There is a growing …
which is extensively used in biomedical and biotechnological context. There is a growing …
Nanosecond pulsed electric fields act as a novel cellular stress that induces translational suppression accompanied by eIF2α phosphorylation and 4E-BP1 …
K Morotomi-Yano, S Oyadomari, H Akiyama… - Experimental cell …, 2012 - Elsevier
Recent advances in electrical engineering enable the generation of ultrashort electric fields,
namely nanosecond pulsed electric fields (nsPEFs). Contrary to conventional electric fields …
namely nanosecond pulsed electric fields (nsPEFs). Contrary to conventional electric fields …
Irreversible electroporation inhibits pro-cancer inflammatory signaling in triple negative breast cancer cells
Low-level electric fields have been demonstrated to induce spatial re-distribution of cell
membrane receptors when applied for minutes or hours. However, there is limited literature …
membrane receptors when applied for minutes or hours. However, there is limited literature …
Nanosecond electric pulse effects on gene expression
L Chopinet, T Batista-Napotnik, A Montigny… - The Journal of …, 2013 - Springer
Gene electrotransfection using micro-or millisecond electric pulses is a well-established
method for safe gene transfer. For efficient transfection, plasmid DNA has to reach the …
method for safe gene transfer. For efficient transfection, plasmid DNA has to reach the …